Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KU528_RS09440 Genome accession   NZ_CP077865
Coordinates   1914651..1915220 (+) Length   189 a.a.
NCBI ID   WP_000872872.1    Uniprot ID   A0AB73JJN0
Organism   Staphylococcus aureus strain 370     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1909651..1920220
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU528_RS09415 (KU528_09370) cysE 1910864..1911511 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  KU528_RS09420 (KU528_09375) cysS 1911495..1912895 (+) 1401 WP_000631977.1 cysteine--tRNA ligase -
  KU528_RS09425 (KU528_09380) - 1912888..1913292 (+) 405 WP_000370186.1 Mini-ribonuclease 3 -
  KU528_RS09430 (KU528_09385) rlmB 1913300..1914046 (+) 747 WP_000390339.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KU528_RS09435 (KU528_09390) - 1914046..1914570 (+) 525 WP_000664738.1 NYN domain-containing protein -
  KU528_RS09440 (KU528_09395) sigH 1914651..1915220 (+) 570 WP_000872872.1 sigma-70 family RNA polymerase sigma factor Regulator
  KU528_RS09445 (KU528_09400) rpmG 1915335..1915478 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  KU528_RS09450 (KU528_09405) secE 1915534..1915716 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KU528_RS09455 (KU528_09410) nusG 1915729..1916277 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  KU528_RS09460 (KU528_09415) rplK 1916458..1916880 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  KU528_RS09465 (KU528_09420) rplA 1917088..1917780 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  KU528_RS09470 (KU528_09425) rplJ 1918052..1918552 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  KU528_RS09475 (KU528_09430) rplL 1918595..1918963 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KU528_RS09480 (KU528_09435) - 1919138..1919746 (+) 609 WP_000020296.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23079.92 Da        Isoelectric Point: 9.6015

>NTDB_id=584204 KU528_RS09440 WP_000872872.1 1914651..1915220(+) (sigH) [Staphylococcus aureus strain 370]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRIDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=584204 KU528_RS09440 WP_000872872.1 1914651..1915220(+) (sigH) [Staphylococcus aureus strain 370]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAACAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATAGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAGCGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979