Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KU524_RS04605 Genome accession   NZ_CP077863
Coordinates   970826..971395 (-) Length   189 a.a.
NCBI ID   WP_000872872.1    Uniprot ID   A0AB73JJN0
Organism   Staphylococcus aureus strain 371     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 965826..976395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU524_RS04565 (KU524_04555) - 966300..966908 (-) 609 WP_000020296.1 class I SAM-dependent methyltransferase -
  KU524_RS04570 (KU524_04560) rplL 967083..967451 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KU524_RS04575 (KU524_04565) rplJ 967494..967994 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  KU524_RS04580 (KU524_04570) rplA 968266..968958 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  KU524_RS04585 (KU524_04575) rplK 969166..969588 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  KU524_RS04590 (KU524_04580) nusG 969769..970317 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  KU524_RS04595 (KU524_04585) secE 970330..970512 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KU524_RS04600 (KU524_04590) rpmG 970568..970711 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  KU524_RS04605 (KU524_04595) sigH 970826..971395 (-) 570 WP_000872872.1 sigma-70 family RNA polymerase sigma factor Regulator
  KU524_RS04610 (KU524_04600) - 971476..972000 (-) 525 WP_000664738.1 NYN domain-containing protein -
  KU524_RS04615 (KU524_04605) rlmB 972000..972746 (-) 747 WP_000390339.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KU524_RS04620 (KU524_04610) - 972754..973158 (-) 405 WP_000370186.1 Mini-ribonuclease 3 -
  KU524_RS04625 (KU524_04615) cysS 973151..974551 (-) 1401 WP_000631977.1 cysteine--tRNA ligase -
  KU524_RS04630 (KU524_04620) cysE 974535..975182 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23079.92 Da        Isoelectric Point: 9.6015

>NTDB_id=584141 KU524_RS04605 WP_000872872.1 970826..971395(-) (sigH) [Staphylococcus aureus strain 371]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRIDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=584141 KU524_RS04605 WP_000872872.1 970826..971395(-) (sigH) [Staphylococcus aureus strain 371]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAACAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATAGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAGCGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979