Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MW400_RS14910 Genome accession   NZ_CP095533
Coordinates   3173977..3174633 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GN02461     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3168977..3179633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MW400_RS14880 (MW400_14875) yecA 3170228..3170893 (-) 666 WP_000847881.1 UPF0149 family protein YecA -
  MW400_RS14900 (MW400_14895) pgsA 3171543..3172091 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MW400_RS14905 (MW400_14900) uvrC 3172148..3173980 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  MW400_RS14910 (MW400_14905) letA 3173977..3174633 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MW400_RS14915 (MW400_14910) yecU 3174929..3175105 (+) 177 WP_000590347.1 protein YecU -
  MW400_RS14920 (MW400_14915) yecF 3175092..3175316 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  MW400_RS14925 (MW400_14920) sdiA 3175384..3176106 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  MW400_RS14930 (MW400_14925) tcyN 3176336..3177088 (-) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MW400_RS14935 (MW400_14930) tcyL 3177085..3177753 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  MW400_RS14940 (MW400_14935) dcyD 3177768..3178754 (-) 987 WP_001128229.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=583848 MW400_RS14910 WP_000611328.1 3173977..3174633(-) (letA) [Escherichia coli strain GN02461]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=583848 MW400_RS14910 WP_000611328.1 3173977..3174633(-) (letA) [Escherichia coli strain GN02461]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482