Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MW397_RS13550 Genome accession   NZ_CP095529
Coordinates   2826181..2826837 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GN06156     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2821181..2831837
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MW397_RS13520 (MW397_13515) yecA 2822432..2823097 (-) 666 WP_000847881.1 UPF0149 family protein YecA -
  MW397_RS13540 (MW397_13535) pgsA 2823747..2824295 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MW397_RS13545 (MW397_13540) uvrC 2824352..2826184 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  MW397_RS13550 (MW397_13545) letA 2826181..2826837 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MW397_RS13555 (MW397_13550) yecU 2827133..2827309 (+) 177 WP_001307856.1 protein YecU -
  MW397_RS13560 (MW397_13555) yecF 2827296..2827520 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  MW397_RS13565 (MW397_13560) sdiA 2827587..2828309 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  MW397_RS13570 (MW397_13565) tcyN 2828539..2829291 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MW397_RS13575 (MW397_13570) tcyL 2829288..2829956 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  MW397_RS13580 (MW397_13575) dcyD 2829971..2830957 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=583759 MW397_RS13550 WP_000611328.1 2826181..2826837(-) (letA) [Escherichia coli strain GN06156]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=583759 MW397_RS13550 WP_000611328.1 2826181..2826837(-) (letA) [Escherichia coli strain GN06156]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGTGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482