Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MU520_RS06535 Genome accession   NZ_CP095463
Coordinates   1326155..1327924 (-) Length   589 a.a.
NCBI ID   WP_024409440.1    Uniprot ID   -
Organism   Streptococcus suis strain TJS56     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1321155..1332924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MU520_RS06515 - 1323259..1323417 (-) 159 WP_015646905.1 hypothetical protein -
  MU520_RS06520 obgE 1323792..1325105 (-) 1314 WP_015646906.1 GTPase ObgE -
  MU520_RS06525 - 1325311..1325439 (-) 129 WP_002943675.1 DUF4044 domain-containing protein -
  MU520_RS06530 - 1325611..1325994 (-) 384 WP_032514712.1 hypothetical protein -
  MU520_RS06535 uvrC 1326155..1327924 (-) 1770 WP_024409440.1 excinuclease ABC subunit UvrC Machinery gene
  MU520_RS06540 - 1328166..1328909 (+) 744 WP_011922278.1 ABC transporter ATP-binding protein -
  MU520_RS06545 - 1328906..1330516 (+) 1611 WP_015646909.1 hypothetical protein -
  MU520_RS06550 - 1330539..1330982 (-) 444 WP_002935466.1 VOC family protein -
  MU520_RS06555 ldcB 1331072..1331827 (-) 756 WP_015646910.1 LD-carboxypeptidase LdcB/DacB -
  MU520_RS06560 - 1332333..1332581 (-) 249 WP_015646911.1 phage holin -

Sequence

Protein


Download         Length: 589 a.a.        Molecular weight: 67659.85 Da        Isoelectric Point: 9.1627

>NTDB_id=583029 MU520_RS06535 WP_024409440.1 1326155..1327924(-) (uvrC) [Streptococcus suis strain TJS56]
MNDLIKHKLELLPDSPGCYLHKNKYGKIIYVGKAKNLRNRVRSYFRGAHDTKTEALVAEIADFEFIVTDSNIEALLLEIN
LIQENKPRYNVMLKDDKSYPFIKITKERHPRLLITRQIKKDGGQYFGPYPDVGAANQTLKLLERLYPFRKCKLPENKYCL
YYHLGQCLAHGENLPSLSDYDKMAKEVAQFLTGHDDKIVKEVQDKMKAAAGNLEFEKAAEYRDVLQSISTLRTKQRVMAH
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERNVNLFPYYNDADEDFLTYIGQFYRDQQHLIPSEVLIPQDIDQEAVEAL
VDTKVIKPQRGEKKQLINLATKNARVSLEQKFNLLEKNLEKTYGAVENIGQLLGIPTPVRIEAFDNSNIMGTSPVSAMVV
FENGVPNKKEYRKYKIKTVEGPDDYASMREVLQRRYSRVLRDGLTPPDLIIIDGGQGQVNIAKQVIEQELGMSIPIAGLQ
KNDKHQTHELLFGNPLEVVELPRNSQEFFLLHRIQDEVHRFAIEFHRQVRSKNSFSSKLDGIEGLGPKRKQALMKHFKSI
GNIQSASLQEIAEAGVPYKVAELVKEKLK

Nucleotide


Download         Length: 1770 bp        

>NTDB_id=583029 MU520_RS06535 WP_024409440.1 1326155..1327924(-) (uvrC) [Streptococcus suis strain TJS56]
ATGAACGATTTGATCAAGCATAAATTGGAGTTACTACCAGATAGCCCTGGCTGTTACCTCCATAAAAACAAGTACGGAAA
GATTATCTATGTGGGCAAGGCCAAAAACCTACGCAATCGGGTGCGGTCTTATTTTCGTGGTGCCCATGATACCAAGACAG
AGGCCTTAGTAGCTGAAATTGCCGATTTTGAATTTATCGTGACAGATTCCAATATCGAGGCACTCTTGTTGGAAATCAAT
CTGATTCAGGAAAACAAGCCTCGCTATAACGTCATGCTTAAGGATGACAAGTCCTATCCCTTCATCAAGATTACCAAGGA
ACGCCATCCACGGCTGCTCATTACACGGCAGATTAAGAAGGACGGTGGTCAGTATTTTGGTCCCTATCCAGATGTGGGTG
CGGCCAACCAGACCCTCAAACTATTGGAGCGCCTCTATCCTTTCCGCAAGTGTAAATTACCTGAGAACAAGTACTGTCTT
TATTATCATTTGGGGCAATGTTTAGCACACGGGGAAAACCTGCCCAGCCTGTCTGACTATGACAAGATGGCCAAGGAAGT
GGCCCAGTTCTTGACGGGTCATGATGATAAGATTGTCAAGGAAGTTCAGGACAAGATGAAGGCTGCTGCTGGCAATTTGG
AATTTGAAAAGGCTGCGGAATACCGAGATGTCCTGCAATCCATTTCAACCCTGAGAACCAAGCAACGTGTCATGGCACAT
GACTTACAAAACCGAGATGTCTTTGGTTATTATGTAGACAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTTCGGCAGGG
GAAACTGATTGAGCGGAATGTCAATCTTTTTCCATACTATAATGATGCGGACGAAGATTTTTTGACCTACATTGGTCAGT
TTTACAGGGACCAGCAACATTTGATTCCCTCAGAGGTCTTGATACCGCAGGATATTGACCAAGAAGCCGTAGAAGCTCTG
GTAGATACCAAGGTCATCAAGCCTCAGCGTGGCGAGAAGAAGCAGCTCATCAATCTGGCAACCAAGAATGCGCGTGTTAG
TCTGGAGCAGAAGTTTAATCTTTTGGAGAAAAATCTGGAGAAGACCTACGGTGCTGTGGAGAATATCGGTCAGCTTTTGG
GGATTCCGACGCCTGTGCGGATTGAGGCTTTCGATAACTCCAACATCATGGGTACCAGTCCTGTGTCGGCTATGGTGGTC
TTTGAAAATGGGGTGCCTAATAAAAAAGAATACCGCAAGTACAAGATTAAGACGGTGGAGGGACCAGACGATTATGCCTC
CATGCGGGAAGTTTTGCAGCGGCGGTACAGTCGGGTACTGCGGGACGGTTTGACACCGCCTGATTTGATTATCATTGACG
GTGGTCAGGGGCAGGTTAACATTGCCAAGCAGGTCATCGAGCAGGAGTTAGGCATGTCCATTCCCATTGCAGGTTTGCAG
AAGAATGACAAGCACCAGACACACGAATTGCTCTTTGGAAATCCCTTAGAGGTGGTTGAACTACCCCGTAATTCTCAGGA
ATTTTTCCTTCTTCATCGAATTCAAGATGAAGTGCACCGATTTGCCATTGAGTTTCATCGTCAGGTACGTTCTAAAAATT
CTTTCTCATCTAAATTGGATGGCATAGAAGGTTTGGGACCAAAACGCAAGCAGGCTCTGATGAAGCATTTCAAGTCTATT
GGCAATATCCAGTCAGCAAGTTTGCAGGAAATCGCAGAAGCAGGAGTGCCGTATAAGGTGGCGGAGTTGGTCAAGGAGAA
GTTGAAGTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

UvrB/uvrC motif (UVR)

(196-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

77.551

99.83

0.774
  uvrC Streptococcus pneumoniae R6

77.211

99.83

0.771
  uvrC Streptococcus pneumoniae D39

77.211

99.83

0.771