NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	MUY23_RS05295	Genome accession	NZ_CP095162
Coordinates	1056004..1056675 (-)	Length	223 a.a.
NCBI ID	WP_009909965.1	Uniprot ID	-
Organism	Streptococcus suis strain TJS75
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1051004..1061675

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUY23_RS05275	coaA	1051590..1052510 (+)	921	WP_002935283.1	type I pantothenate kinase	-
MUY23_RS05280	rpsT	1052569..1052817 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
MUY23_RS05285	-	1053079..1054308 (-)	1230	WP_002935288.1	transglutaminase domain-containing protein	-
MUY23_RS05290	ciaH	1054632..1056011 (-)	1380	WP_002935290.1	HAMP domain-containing sensor histidine kinase	Regulator
MUY23_RS05295	ciaR	1056004..1056675 (-)	672	WP_009909965.1	response regulator transcription factor	Regulator
MUY23_RS05300	-	1056869..1057249 (-)	381	WP_002935294.1	hypothetical protein	-
MUY23_RS05305	-	1057634..1058836 (+)	1203	WP_002935295.1	IS110-like element ISSsu7 family transposase	-
MUY23_RS05310	phoU	1059038..1059694 (-)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
MUY23_RS05315	pstB	1059723..1060481 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
MUY23_RS05320	pstB	1060493..1061296 (-)	804	WP_002937615.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

Download Length: 223 a.a. Molecular weight: 25290.00 Da Isoelectric Point: 4.2183

                                >NTDB_id=582745 MUY23_RS05295 WP_009909965.1 1056004..1056675(-) (ciaR) [Streptococcus suis strain TJS75]

MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA

KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY

FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

Download Length: 672 bp

                                >NTDB_id=582745 MUY23_RS05295 WP_009909965.1 1056004..1056675(-) (ciaR) [Streptococcus suis strain TJS75]

ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT

TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT

TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAATTACGTGAAAAAGGTGTTACGACACCTGTTCTGATTACAACAGCC

AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA

ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG

TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGATCTACTAGTTTAT

TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT

TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTTGGGGAAAATCTTCAAACCCTGC

GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363

Detailed information NTG0582745