Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   VB13_RS01405 Genome accession   NZ_CP077685
Coordinates   264255..265325 (+) Length   356 a.a.
NCBI ID   WP_009880666.1    Uniprot ID   Q54910
Organism   Streptococcus pyogenes strain M49 591     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 259255..270325
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VB13_RS01390 (VB13_01445) amiA 259783..261753 (+) 1971 WP_012560447.1 peptide ABC transporter substrate-binding protein Regulator
  VB13_RS01395 (VB13_01450) amiC 261818..263320 (+) 1503 WP_009880667.1 ABC transporter permease Regulator
  VB13_RS01400 (VB13_01455) amiD 263320..264246 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  VB13_RS01405 (VB13_01460) amiE 264255..265325 (+) 1071 WP_009880666.1 ABC transporter ATP-binding protein Regulator
  VB13_RS01410 (VB13_01465) amiF 265318..266241 (+) 924 WP_219050309.1 ATP-binding cassette domain-containing protein Regulator
  VB13_RS08825 - 266496..266815 (-) 320 Protein_231 IS3 family transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39645.74 Da        Isoelectric Point: 5.8952

>NTDB_id=582225 VB13_RS01405 WP_009880666.1 264255..265325(+) (amiE) [Streptococcus pyogenes strain M49 591]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQGLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=582225 VB13_RS01405 WP_009880666.1 264255..265325(+) (amiE) [Streptococcus pyogenes strain M49 591]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGGTTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q54910

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537