Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MUK76_RS10080 Genome accession   NZ_CP095083
Coordinates   2127374..2128030 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC6868     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2122374..2133030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUK76_RS10050 (MUK76_10050) dcyD 2123253..2124239 (+) 987 WP_001128228.1 D-cysteine desulfhydrase -
  MUK76_RS10055 (MUK76_10055) tcyL 2124254..2124922 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  MUK76_RS10060 (MUK76_10060) tcyN 2124919..2125671 (+) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MUK76_RS10065 (MUK76_10065) sdiA 2125901..2126623 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  MUK76_RS10070 (MUK76_10070) yecF 2126691..2126915 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  MUK76_RS10075 (MUK76_10075) yecU 2126902..2127078 (-) 177 WP_000590347.1 protein YecU -
  MUK76_RS10080 (MUK76_10080) letA 2127374..2128030 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MUK76_RS10085 (MUK76_10085) uvrC 2128027..2129859 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  MUK76_RS10090 (MUK76_10090) pgsA 2129916..2130464 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MUK76_RS10110 (MUK76_10110) yecA 2131114..2131779 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=581928 MUK76_RS10080 WP_000611328.1 2127374..2128030(+) (letA) [Escherichia coli strain EC6868]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=581928 MUK76_RS10080 WP_000611328.1 2127374..2128030(+) (letA) [Escherichia coli strain EC6868]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482