Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MP619_RS09180 Genome accession   NZ_CP095081
Coordinates   1828587..1829228 (-) Length   213 a.a.
NCBI ID   WP_014612503.1    Uniprot ID   A0A9X9QU89
Organism   Streptococcus dysgalactiae strain WJ001     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1823587..1834228
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS09160 (MP619_09130) - 1824961..1825602 (+) 642 WP_129556118.1 YigZ family protein -
  MP619_RS09165 (MP619_09135) cysK 1825703..1826638 (+) 936 WP_129556119.1 cysteine synthase A -
  MP619_RS09170 (MP619_09140) - 1826791..1827150 (-) 360 WP_129556120.1 S1 RNA-binding domain-containing protein -
  MP619_RS09175 (MP619_09145) - 1827150..1828550 (-) 1401 WP_129556121.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  MP619_RS09180 (MP619_09150) vraR 1828587..1829228 (-) 642 WP_014612503.1 response regulator transcription factor Regulator
  MP619_RS09185 (MP619_09155) - 1829221..1830225 (-) 1005 WP_129556123.1 sensor histidine kinase -
  MP619_RS09190 (MP619_09160) liaF 1830222..1830914 (-) 693 WP_129556124.1 cell wall-active antibiotics response protein LiaF -
  MP619_RS09195 (MP619_09165) pknB 1831041..1832936 (-) 1896 WP_003052158.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  MP619_RS09200 (MP619_09170) - 1832933..1833673 (-) 741 WP_003061786.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23806.38 Da        Isoelectric Point: 4.7966

>NTDB_id=581859 MP619_RS09180 WP_014612503.1 1828587..1829228(-) (vraR) [Streptococcus dysgalactiae strain WJ001]
MSNIRVILVDDHEMVRMGLKSFLNLQPDIDVIGEASNGREGVELALALKPDVLVMDLVMPELGGVEATLEILDKWKDAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=581859 MP619_RS09180 WP_014612503.1 1828587..1829228(-) (vraR) [Streptococcus dysgalactiae strain WJ001]
ATGAGTAACATAAGAGTGATACTAGTGGATGATCATGAAATGGTCCGTATGGGACTTAAAAGTTTTTTGAATTTACAACC
AGATATCGACGTTATTGGCGAAGCTTCTAATGGACGTGAGGGAGTTGAGTTGGCCTTAGCCTTAAAACCAGATGTACTGG
TTATGGATTTGGTGATGCCAGAATTAGGTGGTGTTGAGGCGACCTTGGAAATCCTCGATAAGTGGAAAGATGCCAAAGTA
TTGGTCTTGACTTCTTATTTGGACAATGAGAAAATTTACCCTGTCATTGATGCTGGTGCTAAAGGTTACATGTTAAAGAC
TTCTAGTGCAGCCGAAATTCTAAATGCTATTCGGAAAGTTTCAAAAGGTGAATTGGCCATTGAAACAGAGGTAGACAAAA
AAATTAAAGCGCATGATCAACACCCTGATTTGCATGAAGAGCTAACCGCGCGCGAGTATGATATTCTACATCTTTTAGCT
AAAGGGTATGATAATCAAACTATAGCGGATGAACTTTTCATCTCCTTGAAAACCGTTAAAACGCATGTATCTAATATTCT
TGCTAAACTAGAAGTTGATGACCGAACTCAAGCTGTTGTATACGCTTTCCGACACCATTTAGTCCCCCAAGATGATAATT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9QU89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.691

97.183

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376