Detailed information NTG0058185

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: SPN034183_RS08645
• Genome accession: NC_021028
• Coordinates: 1613583..1614242 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565024.1
• Uniprot ID: A0A4J1XTA1
• Organism: Streptococcus pneumoniae SPN034183
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1608583..1619242

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN034183_RS08620 (SPN034183_15880)	-	1608888..1609205 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
SPN034183_RS08625 (SPN034183_15890)	-	1609220..1610116 (-)	897	WP_000825665.1	PEP phosphonomutase	-
SPN034183_RS08630 (SPN034183_15900)	-	1610119..1611381 (-)	1263	WP_000413345.1	PTS sugar transporter subunit IIC	-
SPN034183_RS08635 (SPN034183_15910)	-	1611661..1612839 (+)	1179	WP_000175878.1	ROK family transcriptional regulator	-
SPN034183_RS08640 (SPN034183_15920)	-	1613067..1613513 (-)	447	WP_000155412.1	GNAT family N-acetyltransferase	-
SPN034183_RS08645 (SPN034183_15930)	cclA/cilC	1613583..1614242 (+)	660	WP_000565024.1	A24 family peptidase	Machinery gene
SPN034183_RS08650 (SPN034183_15940)	-	1614294..1615445 (-)	1152	WP_000481758.1	XRE family transcriptional regulator	-
SPN034183_RS08655 (SPN034183_15950)	-	1615460..1616191 (-)	732	WP_000934017.1	hypothetical protein	-
SPN034183_RS12790	-	1616420..1616521 (+)	102	Protein_1662	prepilin peptidase	-
SPN034183_RS08660 (SPN034183_15960)	trpA	1616493..1617269 (-)	777	WP_001127028.1	tryptophan synthase subunit alpha	-
SPN034183_RS08665 (SPN034183_15970)	trpB	1617262..1618485 (-)	1224	WP_000331297.1	tryptophan synthase subunit beta	-
SPN034183_RS08670 (SPN034183_15980)	-	1618463..1619062 (-)	600	WP_000169899.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24951.16 Da
• Isoelectric Point: 8.2409

>NTDB_id=58185 SPN034183_RS08645 WP_000565024.1 1613583..1614242(+) (cclA/cilC) [Streptococcus pneumoniae SPN034183]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWKLLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILITSSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=58185 SPN034183_RS08645 WP_000565024.1 1613583..1614242(+) (cclA/cilC) [Streptococcus pneumoniae SPN034183]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGAAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAACTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

3D structure

• AlphaFold DB: A0A4J1XTA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	96.804	100	0.968
cclA/cilC	Streptococcus pneumoniae Rx1	95.434	100	0.954
cclA/cilC	Streptococcus pneumoniae D39	95.434	100	0.954
cclA/cilC	Streptococcus pneumoniae R6	95.434	100	0.954
cclA/cilC	Streptococcus mitis SK321	91.324	100	0.913
cclA/cilC	Streptococcus mitis NCTC 12261	85.388	100	0.854