Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUK52_RS14775 Genome accession   NZ_CP095011
Coordinates   3393139..3393798 (+) Length   219 a.a.
NCBI ID   WP_284576934.1    Uniprot ID   -
Organism   Streptomyces sp. 2P-4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3388139..3398798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUK52_RS14755 - 3388486..3389706 (+) 1221 WP_284576928.1 acyltransferase -
  MUK52_RS14760 - 3389717..3391033 (+) 1317 WP_284576930.1 sensor histidine kinase -
  MUK52_RS14765 vraR 3391043..3391720 (+) 678 WP_284576932.1 response regulator transcription factor Regulator
  MUK52_RS14770 - 3391808..3393142 (+) 1335 WP_114053475.1 histidine kinase -
  MUK52_RS14775 vraR 3393139..3393798 (+) 660 WP_284576934.1 response regulator transcription factor Regulator
  MUK52_RS14780 - 3393853..3395049 (+) 1197 WP_284576937.1 cytochrome P450 -
  MUK52_RS14785 - 3395126..3396364 (+) 1239 WP_114053472.1 hypothetical protein -
  MUK52_RS14790 - 3396348..3397154 (-) 807 WP_114058376.1 diacylglycerol kinase -
  MUK52_RS14795 - 3397339..3398622 (+) 1284 WP_114053471.1 adenylosuccinate synthase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23492.22 Da        Isoelectric Point: 4.6221

>NTDB_id=581759 MUK52_RS14775 WP_284576934.1 3393139..3393798(+) (vraR) [Streptomyces sp. 2P-4]
MTIRVLIVDDQMMVREGFSVLLNAMDGIEVVGEAVDGREAVAQVAALGPDVVLMDVRMPVMNGLEATREIAAMGTDAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLAEGVRVVASGEALLAPTVTKRLISEFSRLSAAPRPVDASRVGELTDRE
TEVLVLIAQGLSNAEIADRLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYETRLVTPA

Nucleotide


Download         Length: 660 bp        

>NTDB_id=581759 MUK52_RS14775 WP_284576934.1 3393139..3393798(+) (vraR) [Streptomyces sp. 2P-4]
ATGACGATCAGGGTTCTCATCGTCGACGACCAGATGATGGTCCGGGAGGGCTTCTCGGTCCTGCTGAACGCGATGGACGG
CATCGAGGTGGTCGGCGAGGCCGTCGACGGGCGGGAGGCCGTCGCGCAGGTGGCGGCGCTCGGTCCGGACGTGGTGCTGA
TGGACGTCCGGATGCCGGTGATGAACGGGCTGGAGGCCACGCGGGAGATCGCCGCCATGGGCACGGACGCGAAGGTGCTG
GTCCTGACGACCTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGGGCCGGGGCGTCCGGGTTCCTGCTGAAGGACGC
CTCCGCCAGGCAACTGGCCGAGGGGGTGCGGGTGGTGGCGTCCGGGGAGGCGCTGCTGGCGCCGACGGTGACCAAGCGGC
TGATCTCGGAGTTCTCACGGCTGTCCGCGGCCCCCCGGCCGGTCGACGCTTCCAGGGTGGGGGAGTTGACGGACCGGGAG
ACGGAGGTGCTCGTCCTGATCGCGCAGGGCCTCTCCAATGCGGAGATCGCGGACCGGCTGGTGGTGGCCGAGTCCACCAT
CAAGACGCACGTCAGCCGGATCCTGGTGAAGCTGGGCCTGCGCGACCGGACGCAGGCGGCGGTCTTCGCCTACGAGACCC
GCCTCGTCACCCCCGCATAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.981

98.63

0.434
  degU Bacillus subtilis subsp. subtilis str. 168

42.152

100

0.429