Detailed information NTG0581753

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: MUK52_RS13375
• Genome accession: NZ_CP095011
• Coordinates: 3110861..3111985 (+)
• Length: 374 a.a.
• NCBI ID: WP_114053587.1
• Uniprot ID: A0A344TUQ2
• Organism: Streptomyces sp. 2P-4
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3105861..3116985

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUK52_RS13355	-	3106241..3107095 (+)	855	WP_284576422.1	hypothetical protein	-
MUK52_RS13360	-	3107147..3107359 (-)	213	WP_284576425.1	antitoxin	-
MUK52_RS13365	-	3107448..3109160 (-)	1713	WP_284576428.1	hypothetical protein	-
MUK52_RS13370	radA/sms	3109299..3110711 (+)	1413	WP_114053588.1	DNA repair protein RadA	Machinery gene
MUK52_RS13375	disA	3110861..3111985 (+)	1125	WP_114053587.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
MUK52_RS13380	-	3112040..3112834 (-)	795	WP_350206362.1	hypothetical protein	-
MUK52_RS13385	-	3113004..3113618 (+)	615	WP_114053585.1	phosphatase PAP2 family protein	-
MUK52_RS13390	-	3113641..3114594 (+)	954	WP_284576435.1	A/G-specific adenine glycosylase	-
MUK52_RS13395	-	3114766..3115338 (+)	573	WP_114053583.1	SigE family RNA polymerase sigma factor	-
MUK52_RS13400	-	3115377..3116012 (+)	636	WP_114058394.1	hypothetical protein	-
MUK52_RS13405	cseB	3116114..3116818 (+)	705	WP_114053582.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40299.31 Da
• Isoelectric Point: 5.1204

>NTDB_id=581753 MUK52_RS13375 WP_114053587.1 3110861..3111985(+) (disA) [Streptomyces sp. 2P-4]
MAAKDGAAASGKSGASSRQEAMMRASLSAVAPGQPLRDGLERIVRGNTGGLIVLGMDKAVEAMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDLTKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVVSVSQSMRLIALYVNGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVEEALPALDALTHPELLELGIVARALGYTGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAAGVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=581753 MUK52_RS13375 WP_114053587.1 3110861..3111985(+) (disA) [Streptomyces sp. 2P-4]
GTGGCAGCCAAGGACGGGGCAGCAGCATCCGGGAAGTCGGGCGCGAGCTCCAGGCAGGAGGCCATGATGCGTGCCTCCCT
GAGCGCGGTCGCACCCGGCCAGCCCCTGCGCGACGGCCTGGAGAGGATCGTCCGCGGCAACACCGGCGGCCTGATCGTCC
TCGGCATGGACAAGGCCGTCGAGGCGATGTGCACGGGCGGTTTCGTCCTGGACGTGGAGTTCACCGCGACCCGGCTGCGG
GAGCTGTGCAAGCTCGACGGCGCACTCATCCTCGACAAGGACCTCACCAAGATCCTGCGGGCCGGCGTGCAGCTGGTCCC
GGACGCCTCGATCCCGACGGAGGAGACCGGCACCCGGCACCGCACCGCGGACCGCGTCTCCAAGCAGTGCGGGTTCCCCG
TCGTGTCCGTCTCGCAGTCGATGCGGCTGATCGCCCTGTACGTGAACGGGGAGCGCCGCGTCCTGGAGGAGTCGGGCGCG
ATCCTGTCCCGGGCCAACCAGGCGCTCGCCACGCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTCACGGTGCGCGACGTCACGGCCGTCGCGCAGCGGCTGGAAATGGTCCGCCGGATCG
CGACGGAAATCGCGGAGTACGTGGTCGAGCTGGGCACGGACGGGCGACTGCTGTCGCTCCAGCTGGACGAGCTGACGGTC
GGGATCGAGCAGGAGCGGGAGCTCGTCATCCGGGACTACGTGCCCGAGCCGACGGCCAAGCGGTCGCGCACCGTCGAGGA
GGCTCTGCCGGCCCTGGACGCGCTGACGCACCCGGAGCTGCTGGAGCTGGGCATCGTGGCGCGGGCGCTGGGGTACACGG
GCTCGCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTACCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGCGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCGGCCGGCGTGGACGACCTCCAGGCCGTCGA
CGGGGTCGGCGAGGCCCGCGCCCGCAGCGTCCGCGAGGGGCTGTCCCGCCTGGCGGAGTCCTCGATCCTGGAACGCTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

3D structure

• AlphaFold DB: A0A344TUQ2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436