Detailed information    

insolico Bioinformatically predicted

Overview

Name   hdrM   Type   Regulator
Locus tag   I6L88_RS00525 Genome accession   NZ_CP077404
Coordinates   99386..100072 (-) Length   228 a.a.
NCBI ID   WP_002268420.1    Uniprot ID   -
Organism   Streptococcus mutans strain FDAARGOS 1458     
Function   repress competence development; negative regulate HdrR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 94386..105072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L88_RS00495 (I6L88_00495) - 96360..96563 (-) 204 WP_002280327.1 hypothetical protein -
  I6L88_RS00500 (I6L88_00500) - 96868..97113 (+) 246 WP_002263367.1 hypothetical protein -
  I6L88_RS00505 (I6L88_00505) rpsF 97269..97559 (+) 291 WP_002261866.1 30S ribosomal protein S6 -
  I6L88_RS00510 (I6L88_00510) ssbA 97577..98071 (+) 495 WP_002261867.1 single-stranded DNA-binding protein Machinery gene
  I6L88_RS00515 (I6L88_00515) rpsR 98101..98340 (+) 240 WP_000068664.1 30S ribosomal protein S18 -
  I6L88_RS00520 (I6L88_00520) - 98659..99378 (+) 720 WP_002280414.1 TraX family protein -
  I6L88_RS00525 (I6L88_00525) hdrM 99386..100072 (-) 687 WP_002268420.1 hdrR negative regulator HdrM Regulator
  I6L88_RS00530 (I6L88_00530) hdrR 100069..100425 (-) 357 WP_002280415.1 LytTR family transcriptional regulator HdrR Regulator
  I6L88_RS00535 (I6L88_00535) - 100564..101226 (-) 663 WP_002265267.1 DUF1129 domain-containing protein -
  I6L88_RS00540 (I6L88_00540) - 101508..102452 (-) 945 WP_002262667.1 magnesium transporter CorA family protein -
  I6L88_RS00545 (I6L88_00545) - 102852..103073 (-) 222 WP_018110215.1 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26101.17 Da        Isoelectric Point: 6.7581

>NTDB_id=581286 I6L88_RS00525 WP_002268420.1 99386..100072(-) (hdrM) [Streptococcus mutans strain FDAARGOS 1458]
MKKNYFWYGLLGLLALYLITIAFIPGFHIFFSNMLMLALFFMLIALSNRSIFFFFLALGFLSIYLKDIFHFDYSTGPLFT
GIIIIGVILNSFLKPHYSYSYKGNHYFNMKQNANYIDNETDVFLKTLFSENTSYVTSQELNKIIIDTKFGEQSVDLSQAQ
FMTDSPEIHIDISFGETNLRIPNNWKIINKTHSPFASISFSGFPSTNGDFINVTLTGTVAMGSLNIQY

Nucleotide


Download         Length: 687 bp        

>NTDB_id=581286 I6L88_RS00525 WP_002268420.1 99386..100072(-) (hdrM) [Streptococcus mutans strain FDAARGOS 1458]
ATGAAAAAAAATTATTTTTGGTACGGTCTGCTTGGGCTTCTCGCACTTTACCTTATTACTATTGCTTTTATCCCGGGATT
TCATATTTTCTTTAGCAACATGTTGATGTTGGCCCTGTTCTTTATGTTAATAGCTTTGAGTAACAGGAGTATCTTCTTTT
TCTTTCTAGCCTTAGGTTTTCTTAGTATCTACTTGAAAGATATCTTTCATTTTGACTATTCTACCGGACCGCTTTTTACG
GGTATAATCATTATCGGCGTTATCTTAAATAGTTTCCTCAAACCACACTATTCTTATTCTTATAAAGGAAATCATTATTT
TAATATGAAACAAAATGCTAACTACATTGATAACGAAACAGATGTCTTTTTAAAAACACTTTTTTCTGAAAATACCAGTT
ATGTGACTTCTCAAGAATTAAATAAAATTATTATTGATACTAAGTTTGGAGAACAATCTGTTGATCTCTCTCAAGCTCAA
TTTATGACAGATTCTCCCGAAATTCATATAGATATTAGCTTTGGTGAAACCAATCTGCGTATTCCAAACAACTGGAAAAT
CATCAATAAAACTCACTCCCCCTTTGCTTCCATTTCATTTTCAGGTTTTCCTAGCACAAATGGTGATTTTATTAACGTTA
CATTGACTGGAACAGTGGCTATGGGATCTCTAAACATTCAATATTAA

Domains

Predicted by InterproScan.

Cell wall-active antibiotics response 4TMS YvqF (LiaF-like_C)

(128-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hdrM Streptococcus mutans UA159

99.123

100

0.991