Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MUO49_RS13345 Genome accession   NZ_CP094924
Coordinates   2670655..2672640 (+) Length   661 a.a.
NCBI ID   WP_000229236.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 18     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2665655..2677640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUO49_RS13315 (MUO49_13300) - 2666698..2666802 (+) 105 WP_001790092.1 hypothetical protein -
  MUO49_RS13320 (MUO49_13305) prfB 2666971..2668081 (+) 1111 WP_014667688.1 peptide chain release factor 2 -
  MUO49_RS13325 (MUO49_13310) - 2668235..2668342 (+) 108 WP_072384807.1 hypothetical protein -
  MUO49_RS13330 (MUO49_13315) - 2668490..2669329 (+) 840 WP_000749383.1 CHAP domain-containing protein -
  MUO49_RS13335 (MUO49_13320) - 2669503..2670153 (+) 651 WP_000538141.1 YfbR-like 5'-deoxynucleotidase -
  MUO49_RS13340 (MUO49_13325) - 2670150..2670386 (+) 237 WP_000638419.1 CsbA family protein -
  MUO49_RS13345 (MUO49_13330) uvrB 2670655..2672640 (+) 1986 WP_000229236.1 excinuclease ABC subunit UvrB Machinery gene
  MUO49_RS13350 (MUO49_13335) uvrA 2672648..2675494 (+) 2847 WP_000662681.1 excinuclease ABC subunit UvrA Machinery gene
  MUO49_RS13355 (MUO49_13340) hprK 2676114..2677046 (+) 933 WP_000958224.1 HPr(Ser) kinase/phosphatase -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 76661.33 Da        Isoelectric Point: 4.9777

>NTDB_id=581207 MUO49_RS13345 WP_000229236.1 2670655..2672640(+) (uvrB) [Staphylococcus aureus strain 18]
MVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQIRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=581207 MUO49_RS13345 WP_000229236.1 2670655..2672640(+) (uvrB) [Staphylococcus aureus strain 18]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCGCAAGCAATTGAAGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCTACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGGAAACCAACGTTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCAGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCTGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGTGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGTGATGTAGTTGAAATATTCCCAGCCTCTAAAGAAGAACTTTGTA
TAAGGGTTGAGTTTTTCGGCGATGAGATTGACCGTATCCGAGAAGTTAACTACCTAACAGGTGAAGTGTTGAAAGAAAGA
GAACATTTTGCGATATTCCCAGCTTCTCACTTCGTAACACGTGAAGAAAAGTTGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAACT
ATGATTTAGAAATGATGCGAGAGATGGGATTCTGTTCAGGAATTGAAAACTATTCCGTACATTTAACTTTGCGACCACTG
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACATTACC
GCAAGTTCGAGGCATGTATAACGGAGACAGAGCGCGTAAACAAGTTTTGGTGGATCATGGGTTTAGATTACCGAGTGCAT
TAGATAACCGTCCACTTAAATTTGAAGAATTTGAAGAAAAGACAAAACAACTTGTGTATGTATCTGCAACGCCTGGACCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATTCAAATAAGGGTTGAGCGTAATGAACGCGTACTTGTTACAA
CGCTCACTAAAAAGATGAGTGAAGATTTAACCACATACATGAAAGAAGCGGGTATTAAAGTTAATTATCTGCATTCAGAA
ATCAAGACATTAGAACGAATCGAAATAATTAGAGACTTACGAATGGGTACATATGATGTTATCGTAGGTATTAATTTATT
AAGAGAGGGTATTGATATACCAGAAGTTTCTCTAGTTGTCATATTAGATGCAGATAAAGAAGGATTTTTACGTTCTAACC
GCTCATTAATTCAAACAATAGGTAGAGCTGCGCGTAACGATAAAGGTGAAGTCATTATGTATGCCGATAAAATGACTGAT
TCGATGAAGTATGCAATTGATGAGACACAACGTCGTCGAGAAATACAGATGAAACATAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(436-546)

Ultra-violet resistance protein B (UvrB)

(553-594)

UvrB/uvrC motif (UVR)

(626-659)

UvrB interaction domain (UvrB_inter)

(161-251)

Type III restriction enzyme, res subunit (ResIII)

(14-140)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

67.688

98.79

0.669
  uvrB Streptococcus pneumoniae D39

67.688

98.79

0.669
  uvrB Streptococcus pneumoniae TIGR4

67.688

98.79

0.669