Detailed information NTG0058063

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: SPN034156_RS10545
• Genome accession: NC_021006
• Coordinates: 1969370..1970020 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387330.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae SPN034156
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1964370..1975020

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN034156_RS10505 (SPN034156_18930)	-	1964853..1965068 (+)	216	WP_001232082.1	YozE family protein	-
SPN034156_RS10510 (SPN034156_18940)	-	1965154..1966122 (+)	969	WP_000658183.1	PhoH family protein	-
SPN034156_RS10515 (SPN034156_18950)	-	1966315..1966815 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
SPN034156_RS10520 (SPN034156_18960)	-	1966818..1967144 (+)	327	Protein_1962	TfoX/Sxy family protein	-
SPN034156_RS12955 (SPN034156_18970)	ald	1967445..1968556 (-)	1112	Protein_1963	alanine dehydrogenase	-
SPN034156_RS10540 (SPN034156_18980)	-	1968733..1969302 (+)	570	WP_000443747.1	GNAT family N-acetyltransferase	-
SPN034156_RS10545 (SPN034156_18990)	comEA/celA/cilE	1969370..1970020 (+)	651	WP_000387330.1	ComEA family DNA-binding protein	Machinery gene
SPN034156_RS10550 (SPN034156_19000)	comEC/celB	1970004..1972244 (+)	2241	WP_000942395.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SPN034156_RS10555	-	1972423..1972611 (+)	189	WP_001809102.1	hypothetical protein	-
SPN034156_RS10560 (SPN034156_19010)	-	1972643..1973230 (+)	588	WP_000933542.1	ABC transporter ATP-binding protein	-
SPN034156_RS10565 (SPN034156_19020)	-	1973234..1974415 (+)	1182	WP_000655956.1	hypothetical protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23229.65 Da
• Isoelectric Point: 5.5171

>NTDB_id=58063 SPN034156_RS10545 WP_000387330.1 1969370..1970020(+) (comEA/celA/cilE) [Streptococcus pneumoniae SPN034156]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=58063 SPN034156_RS10545 WP_000387330.1 1969370..1970020(+) (comEA/celA/cilE) [Streptococcus pneumoniae SPN034156]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae D39	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae R6	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comEA/celA/cilE	Streptococcus mitis NCTC 12261	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis SK321	90.278	100	0.903
comEA	Lactococcus lactis subsp. cremoris KW2	43.172	100	0.454
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361