Detailed information NTG0580385

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: I6L86_RS04880
• Genome accession: NZ_CP077259
• Coordinates: 1040807..1041874 (+)
• Length: 355 a.a.
• NCBI ID: WP_000159550.1
• Uniprot ID: F9HAA0
• Organism: Streptococcus mitis strain FDAARGOS 1456
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1035807..1046874

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L86_RS04865 (I6L86_04865)	amiA3	1036321..1038309 (+)	1989	WP_000749582.1	peptide ABC transporter substrate-binding protein	Regulator
I6L86_RS04870 (I6L86_04870)	amiC	1038376..1039872 (+)	1497	WP_000759915.1	ABC transporter permease	Regulator
I6L86_RS04875 (I6L86_04875)	amiD	1039872..1040798 (+)	927	WP_000103691.1	oligopeptide ABC transporter permease OppC	Regulator
I6L86_RS04880 (I6L86_04880)	amiE	1040807..1041874 (+)	1068	WP_000159550.1	ABC transporter ATP-binding protein	Regulator
I6L86_RS04885 (I6L86_04885)	amiF	1041885..1042811 (+)	927	WP_001291284.1	ATP-binding cassette domain-containing protein	Regulator
I6L86_RS04890 (I6L86_04890)	-	1043215..1044093 (-)	879	WP_001049302.1	LysR family transcriptional regulator	-
I6L86_RS04895 (I6L86_04895)	-	1044221..1044571 (-)	351	WP_000208711.1	helix-turn-helix domain-containing protein	-
I6L86_RS04900 (I6L86_04900)	-	1044845..1046470 (+)	1626	WP_000200491.1	malolactic enzyme	-
I6L86_RS04905 (I6L86_04905)	-	1046672..1046791 (+)	120	Protein_934	IS630 family transposase	-

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39491.07 Da
• Isoelectric Point: 4.8078

>NTDB_id=580385 I6L86_RS04880 WP_000159550.1 1040807..1041874(+) (amiE) [Streptococcus mitis strain FDAARGOS 1456]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFDEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=580385 I6L86_RS04880 WP_000159550.1 1040807..1041874(+) (amiE) [Streptococcus mitis strain FDAARGOS 1456]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGGAAATCTGTTT
TGACAAAGACATTCACAGGTATGCTTGAAGAAAACGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAAGATTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGCGCTAAGATTGCGACTATCTTCCAAGATCCAATGACTAG
TTTGGACCCAATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGGATTCCAGATGCAGATAGACGTTTTGATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCTCTTGCCTGCCGACCTGATGTCTTGATTTGTGATGAGCCAAC
GACTGCCTTGGATGTGACCATCCAAGCTCAGATTATTGATTTGTTGAAATCTTTACAAAACGAGTACCATTTCACAACAA
TCTTTATCACCCACGACCTTGGTGTGGTGGCAAGTATTGCAGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACTGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGTGATGCCTTTGCCT
TGCGTTCTGACTATGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTACTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATTCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: F9HAA0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	87.887	100	0.879
amiE	Streptococcus thermophilus LMG 18311	86.197	100	0.862
amiE	Streptococcus thermophilus LMD-9	86.197	100	0.862
oppD	Streptococcus mutans UA159	54.261	99.155	0.538