Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6L85_RS08195 Genome accession   NZ_CP077248
Coordinates   1649356..1650045 (-) Length   229 a.a.
NCBI ID   WP_111723335.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1455     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1644356..1655045
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L85_RS08175 (I6L85_08175) nrdR 1644758..1645231 (-) 474 WP_008808512.1 transcriptional regulator NrdR -
  I6L85_RS08180 (I6L85_08180) - 1645411..1645827 (+) 417 WP_111723337.1 hypothetical protein -
  I6L85_RS08185 (I6L85_08185) - 1645970..1646785 (-) 816 WP_012000012.1 endonuclease/exonuclease/phosphatase family protein -
  I6L85_RS08190 (I6L85_08190) - 1646803..1648995 (-) 2193 WP_111723336.1 PTS transporter subunit IIBC -
  I6L85_RS08195 (I6L85_08195) covR 1649356..1650045 (-) 690 WP_111723335.1 response regulator transcription factor Regulator
  I6L85_RS08200 (I6L85_08200) gndA 1650058..1651482 (-) 1425 WP_111723334.1 NADP-dependent phosphogluconate dehydrogenase -
  I6L85_RS08205 (I6L85_08205) - 1651618..1653099 (-) 1482 WP_012000008.1 flotillin family protein -
  I6L85_RS08210 (I6L85_08210) - 1653201..1653731 (-) 531 WP_061597297.1 DUF177 domain-containing protein -
  I6L85_RS08215 (I6L85_08215) - 1653829..1654698 (+) 870 WP_061597296.1 Rgg/GadR/MutR family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26275.31 Da        Isoelectric Point: 5.1861

>NTDB_id=580293 I6L85_RS08195 WP_111723335.1 1649356..1650045(-) (covR) [Streptococcus gordonii strain FDAARGOS 1455]
MAKRILLVENEKNLARFIMLELQKESYQVDLAETGQEGLALAKENDYDLLLLNNQFADGTAFAFAQQLSLLKPVAVIIVM
VSREEIADSAEEIQQFAVSYMVKPFIISDLVDKISAIFRGRDFIDQKCSQLKVPTAYRNLRVDLKNHTVYRGDEIIALTR
REYDLLVTLMSSNKVMSREQLLDRVWKYESASETNIVDVYIRYLRSKIDLPGQESYIKTVRGIGYSMQG

Nucleotide


Download         Length: 690 bp        

>NTDB_id=580293 I6L85_RS08195 WP_111723335.1 1649356..1650045(-) (covR) [Streptococcus gordonii strain FDAARGOS 1455]
ATGGCGAAGCGGATTTTATTAGTTGAAAATGAAAAGAATCTAGCACGATTTATCATGCTGGAATTACAAAAGGAAAGTTA
TCAAGTAGATCTAGCGGAAACAGGGCAAGAGGGACTAGCTCTAGCAAAGGAAAACGATTATGATTTACTTTTACTAAATA
ATCAGTTTGCTGATGGAACAGCCTTTGCCTTTGCTCAACAATTAAGTTTATTAAAACCAGTTGCAGTAATCATTGTAATG
GTGAGCCGAGAGGAAATTGCGGATTCGGCTGAAGAGATTCAGCAGTTTGCAGTTTCTTATATGGTAAAACCCTTTATTAT
CAGTGATTTGGTTGATAAGATATCTGCTATCTTTCGTGGACGAGATTTTATTGATCAGAAATGTAGCCAGTTAAAAGTTC
CTACTGCTTATCGTAATTTGCGGGTTGATTTGAAAAATCATACGGTTTATCGAGGGGATGAAATTATTGCTTTGACGAGA
CGAGAGTACGATTTACTAGTGACTCTAATGAGCAGTAATAAGGTGATGAGCCGTGAGCAACTGTTAGATCGAGTGTGGAA
GTATGAAAGTGCATCTGAGACTAATATAGTGGATGTATATATTCGTTACCTCCGTAGTAAAATCGATCTTCCGGGACAAG
AAAGTTATATTAAAACCGTTCGTGGAATTGGTTATTCCATGCAGGGGTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

52.212

98.69

0.515
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.737

99.563

0.445