Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I6L85_RS07700 Genome accession   NZ_CP077248
Coordinates   1543602..1544903 (-) Length   433 a.a.
NCBI ID   WP_111723395.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1455     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1538602..1549903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L85_RS07690 (I6L85_07690) raiA 1542313..1542855 (-) 543 WP_012000104.1 ribosome-associated translation inhibitor RaiA -
  I6L85_RS07695 (I6L85_07695) comFC/cflB 1542940..1543605 (-) 666 WP_111723396.1 ComF family protein Machinery gene
  I6L85_RS07700 (I6L85_07700) comFA/cflA 1543602..1544903 (-) 1302 WP_111723395.1 DEAD/DEAH box helicase Machinery gene
  I6L85_RS07705 (I6L85_07705) - 1544959..1545591 (+) 633 WP_061593780.1 YigZ family protein -
  I6L85_RS07710 (I6L85_07710) cysK 1545689..1546618 (+) 930 WP_008808600.1 cysteine synthase A -
  I6L85_RS07715 (I6L85_07715) - 1546655..1547041 (-) 387 WP_008808599.1 S1 RNA-binding domain-containing protein -
  I6L85_RS07720 (I6L85_07720) - 1547038..1548441 (-) 1404 WP_111723394.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6L85_RS07725 (I6L85_07725) - 1548529..1549161 (-) 633 WP_070494100.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49453.37 Da        Isoelectric Point: 8.2076

>NTDB_id=580287 I6L85_RS07700 WP_111723395.1 1543602..1544903(-) (comFA/cflA) [Streptococcus gordonii strain FDAARGOS 1455]
MLELQDCLGRIFTKEQLPPELLKKAKRISSIFEEKGELFCSRCYSQIDKERNLLPIGAYYCRECILLGRVRSDEDLYYFF
QESFPIISSLKWLGQLTEYQERVSKGLLEGVQSKQDTLVHAVTGAGKTEMIYQVVAQVLDQGGAVCIASPRIDVCLELYR
RLKEDFSCDISLLHGESDPYSRSPLVIATTHQLLKFYQAFDLLIVDEVDAFPYVDNPVLYHAVEQAVKNEGTTIFLTATS
TDELDKKVQKGILKRLSLPRRFHGNPLIIPQKVWLSGLNKDLQREKLPAKLVKYLRKQRKTKFPLLIFASEIKKGQEIKQ
VLQKYFPEENVGFVASTTENRLEIVQDFRDKKISILVTTTILERGVTFPCVDVIVLEANHRLFTRSALVQIGGRVGRSME
RPTGDLLFFHDGTNIQIEKAINEIKAMNREAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=580287 I6L85_RS07700 WP_111723395.1 1543602..1544903(-) (comFA/cflA) [Streptococcus gordonii strain FDAARGOS 1455]
ATGTTAGAATTGCAAGATTGTTTAGGGCGAATTTTTACTAAAGAACAGTTACCTCCTGAACTACTTAAGAAAGCTAAAAG
GATATCATCAATTTTTGAAGAAAAGGGAGAACTTTTTTGTTCTCGCTGCTACAGTCAGATTGATAAGGAAAGAAATTTAT
TACCAATTGGTGCATATTATTGCAGAGAATGCATTCTTCTAGGGAGAGTGCGTAGTGACGAAGATCTTTATTATTTTTTT
CAAGAATCTTTTCCTATAATATCAAGTTTGAAATGGCTCGGCCAATTGACAGAATATCAGGAAAGAGTTTCTAAGGGATT
ACTTGAAGGAGTGCAAAGTAAACAGGATACTTTAGTCCACGCTGTAACTGGAGCAGGAAAAACGGAAATGATCTATCAAG
TGGTTGCTCAGGTGTTAGATCAAGGAGGGGCTGTCTGTATAGCTAGTCCTCGGATAGATGTCTGTTTGGAACTGTACCGA
CGTTTAAAAGAAGATTTTTCATGTGATATTTCCCTATTGCATGGGGAGTCCGACCCCTATTCACGCAGTCCCTTAGTGAT
TGCAACAACTCATCAATTACTAAAATTTTATCAGGCATTTGATTTACTCATTGTTGATGAGGTAGATGCCTTTCCTTATG
TAGATAACCCTGTGCTCTATCATGCTGTCGAGCAAGCAGTAAAAAATGAAGGAACTACAATATTCCTAACGGCTACGTCA
ACTGATGAGCTTGATAAAAAAGTCCAAAAAGGAATTTTGAAAAGATTAAGTTTGCCAAGACGCTTTCATGGAAATCCCTT
GATTATCCCACAAAAAGTATGGCTTTCTGGTCTAAATAAAGACCTCCAAAGAGAAAAACTACCAGCCAAGTTAGTCAAGT
ATCTGAGAAAACAAAGAAAAACAAAATTCCCACTCTTAATTTTTGCTTCAGAAATTAAAAAAGGGCAGGAGATAAAGCAA
GTCTTACAAAAATATTTTCCAGAAGAAAATGTAGGTTTTGTAGCCTCTACAACGGAAAATAGATTAGAAATAGTGCAAGA
TTTTCGAGATAAAAAGATAAGTATATTAGTAACAACTACAATTTTAGAAAGAGGGGTTACTTTTCCATGTGTAGATGTAA
TTGTTTTAGAAGCTAACCATCGTCTCTTTACAAGGAGTGCTTTAGTACAAATTGGCGGGCGAGTAGGAAGAAGTATGGAA
CGACCTACAGGTGACTTACTATTTTTTCATGATGGCACTAATATACAGATAGAAAAAGCAATCAATGAAATTAAAGCAAT
GAACAGAGAGGCCGGATTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-397)

DEAD/DEAH box helicase (DEAD)

(97-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

68.925

98.845

0.681
  comFA/cflA Streptococcus pneumoniae Rx1

68.925

98.845

0.681
  comFA/cflA Streptococcus pneumoniae D39

68.925

98.845

0.681
  comFA/cflA Streptococcus pneumoniae R6

68.925

98.845

0.681
  comFA/cflA Streptococcus mitis NCTC 12261

68.779

98.383

0.677
  comFA/cflA Streptococcus mitis SK321

68.779

98.383

0.677
  comFA Lactococcus lactis subsp. cremoris KW2

53.807

90.993

0.49
  comFA Latilactobacillus sakei subsp. sakei 23K

39.261

100

0.393