Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   I6L85_RS05140 Genome accession   NZ_CP077248
Coordinates   1025956..1027185 (+) Length   409 a.a.
NCBI ID   WP_008808666.1    Uniprot ID   A0AAP2K4Q6
Organism   Streptococcus gordonii strain FDAARGOS 1455     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1012007..1028612 1025956..1027185 within 0


Gene organization within MGE regions


Location: 1012007..1028612
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L85_RS05060 (I6L85_05060) guaC 1012007..1012990 (+) 984 WP_012000563.1 GMP reductase -
  I6L85_RS05065 (I6L85_05065) - 1013171..1013752 (+) 582 WP_111723726.1 xanthine phosphoribosyltransferase -
  I6L85_RS05070 (I6L85_05070) - 1013754..1015019 (+) 1266 WP_037622361.1 nucleobase:cation symporter-2 family protein -
  I6L85_RS05075 (I6L85_05075) - 1015133..1015315 (-) 183 WP_001117401.1 4-oxalocrotonate tautomerase -
  I6L85_RS05080 (I6L85_05080) - 1015437..1016012 (+) 576 WP_111723725.1 thymidine kinase -
  I6L85_RS05085 (I6L85_05085) prfA 1016045..1017124 (+) 1080 WP_012000560.1 peptide chain release factor 1 -
  I6L85_RS05090 (I6L85_05090) prmC 1017124..1017954 (+) 831 WP_008808656.1 peptide chain release factor N(5)-glutamine methyltransferase -
  I6L85_RS05095 (I6L85_05095) - 1017947..1018537 (+) 591 WP_048775981.1 L-threonylcarbamoyladenylate synthase -
  I6L85_RS05100 (I6L85_05100) glyA 1018585..1019847 (+) 1263 WP_008808658.1 serine hydroxymethyltransferase -
  I6L85_RS05105 (I6L85_05105) - 1019849..1020823 (+) 975 WP_111723724.1 nucleoid-associated protein -
  I6L85_RS05110 (I6L85_05110) - 1020823..1021425 (+) 603 WP_045774036.1 lysozyme family protein -
  I6L85_RS05115 (I6L85_05115) - 1021539..1022384 (+) 846 WP_111723723.1 alpha/beta hydrolase -
  I6L85_RS05120 (I6L85_05120) - 1022559..1023518 (+) 960 WP_008808662.1 ROK family glucokinase -
  I6L85_RS05125 (I6L85_05125) - 1023618..1024457 (+) 840 WP_008808663.1 thymidylate synthase -
  I6L85_RS05130 (I6L85_05130) - 1024588..1025088 (+) 501 WP_008808664.1 hypothetical protein -
  I6L85_RS05135 (I6L85_05135) - 1025234..1025746 (+) 513 WP_008808665.1 dihydrofolate reductase -
  I6L85_RS05140 (I6L85_05140) clpX 1025956..1027185 (+) 1230 WP_008808666.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  I6L85_RS05145 (I6L85_05145) yihA 1027195..1027788 (+) 594 WP_008808667.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  I6L85_RS05150 (I6L85_05150) - 1027923..1028612 (+) 690 WP_008808668.1 glucosaminidase domain-containing protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45650.21 Da        Isoelectric Point: 4.4870

>NTDB_id=580274 I6L85_RS05140 WP_008808666.1 1025956..1027185(+) (clpX) [Streptococcus gordonii strain FDAARGOS 1455]
MPTNRNEEMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLHILNHYVIGQER
AKRALAVAVYNHYKRINFHDSREEDDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENESYMQAIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LREPKNALVKQYQALLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSKENVKLVRITKEAVDG
TDKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=580274 I6L85_RS05140 WP_008808666.1 1025956..1027185(+) (clpX) [Streptococcus gordonii strain FDAARGOS 1455]
ATGCCTACCAATCGTAATGAAGAGATGATGGTATATTGTTCATTCTGTGGGAAGAACCAAGATGAGGTTCAAAAGATTAT
TGCGGGTAATAACGCTTTTATTTGTAATGAGTGTGTAGAATTAGCACAAGAAATTATCCGTGAAGAATTAGCCGAAGAAG
TCTTAGCTGACTTGTCAGAGGTTCCAAAACCTCAAGAATTATTGCATATTCTAAACCATTATGTCATCGGTCAAGAACGT
GCTAAAAGAGCGCTAGCTGTAGCGGTATATAATCACTACAAGCGTATTAATTTTCATGACAGTCGCGAAGAAGATGATGT
TGAATTACAAAAATCAAATATCTTAATGATCGGTCCAACGGGATCTGGGAAGACTTTTCTTGCTCAGACCTTAGCTAGAA
GTTTAAATGTGCCTTTTGCTATTGCTGATGCGACAGCTTTAACAGAGGCTGGTTATGTCGGAGAAGACGTTGAAAATATC
CTTTTAAAACTTTTACAGGCGGCTGATTTCAATATTGAACGTGCAGAACGAGGAATCATCTACGTAGATGAGATTGATAA
GATCGCTAAAAAGAGTGAAAATGTTTCTATCACGCGCGATGTATCAGGTGAAGGAGTACAGCAAGCTCTCTTAAAAATTA
TCGAGGGTACTGTAGCAAGTGTTCCGCCTCAAGGAGGTCGCAAACATCCGCAGCAAGAAATGATTCAGGTTGATACCAAA
AATATTCTTTTCATCGTTGGTGGTGCCTTTGATGGGATTGAAGAAATTGTAAAACAACGTTTGGGCGAGAAAATTATTGG
TTTTGGTCAAAATAACAAAGCTATCGATGAAAACGAGTCCTACATGCAGGCTATTATTGCTGAAGATATTCAAAAATTTG
GAATTATTCCTGAATTAATTGGCCGTTTGCCTGTTTTTGCTGCTCTGGAACAACTGACTGTAGATGACTTGGTTCGTATT
CTTCGTGAGCCAAAGAATGCTTTGGTTAAACAATACCAGGCTCTCTTGTCTTACGATGATGTTAAACTAGAGTTTGATGA
TGATGCTTTACAGGAAATCGCGAACAAGGCCATTGAGCGCAAAACTGGGGCCCGTGGTCTACGTTCTATCATCGAAGAAA
CCATGATGGATGTTATGTTTGAAGTTCCAAGTAAAGAAAATGTGAAACTTGTCAGAATTACAAAGGAAGCCGTTGATGGT
ACGGATAAACCAATTTTAGAGACTGCTTGA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

85.575

100

0.856
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.105

98.044

0.57