Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SPN034156_RS04445 Genome accession   NC_021006
Coordinates   824717..825541 (-) Length   274 a.a.
NCBI ID   WP_001036787.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN034156     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 819717..830541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN034156_RS04440 (SPN034156_08030) - 823095..824426 (-) 1332 WP_000390039.1 hemolysin family protein -
  SPN034156_RS04445 (SPN034156_08040) endA 824717..825541 (-) 825 WP_001036787.1 DNA-entry nuclease EndA Machinery gene
  SPN034156_RS04450 (SPN034156_08050) - 825580..825768 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  SPN034156_RS04455 (SPN034156_08060) murA 825761..827044 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SPN034156_RS04460 (SPN034156_08070) - 827068..827298 (-) 231 WP_000250384.1 DUF1146 family protein -
  SPN034156_RS04465 (SPN034156_08080) sepM 827356..828393 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  SPN034156_RS04470 (SPN034156_08090) coaD 828377..828865 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  SPN034156_RS04475 (SPN034156_08100) rsmD 828855..829394 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SPN034156_RS04480 (SPN034156_08110) asnA 829459..830451 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29917.60 Da        Isoelectric Point: 10.1197

>NTDB_id=58019 SPN034156_RS04445 WP_001036787.1 824717..825541(-) (endA) [Streptococcus pneumoniae SPN034156]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQGPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=58019 SPN034156_RS04445 WP_001036787.1 824717..825541(-) (endA) [Streptococcus pneumoniae SPN034156]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGGGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.905

100

0.989
  endA Streptococcus pneumoniae D39

98.905

100

0.989
  endA Streptococcus pneumoniae R6

98.905

100

0.989
  endA Streptococcus pneumoniae TIGR4

98.905

100

0.989

Multiple sequence alignment