Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6L84_RS08500 Genome accession   NZ_CP077224
Coordinates   1731966..1732655 (-) Length   229 a.a.
NCBI ID   WP_045505796.1    Uniprot ID   A0AAW3H5C9
Organism   Streptococcus gordonii strain FDAARGOS 1454     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1726966..1737655
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L84_RS08480 (I6L84_08480) nrdR 1727371..1727844 (-) 474 WP_012000014.1 transcriptional regulator NrdR -
  I6L84_RS08485 (I6L84_08485) - 1728024..1728440 (+) 417 WP_060552991.1 hypothetical protein -
  I6L84_RS08490 (I6L84_08490) - 1728583..1729398 (-) 816 WP_045505802.1 endonuclease/exonuclease/phosphatase family protein -
  I6L84_RS08495 (I6L84_08495) - 1729416..1731608 (-) 2193 WP_060552992.1 PTS transporter subunit IIBC -
  I6L84_RS08500 (I6L84_08500) covR 1731966..1732655 (-) 690 WP_045505796.1 response regulator transcription factor Regulator
  I6L84_RS08505 (I6L84_08505) gndA 1732668..1734092 (-) 1425 WP_060552993.1 NADP-dependent phosphogluconate dehydrogenase -
  I6L84_RS08510 (I6L84_08510) - 1734228..1735709 (-) 1482 WP_060552994.1 flotillin family protein -
  I6L84_RS08515 (I6L84_08515) - 1735812..1736342 (-) 531 WP_012000007.1 DUF177 domain-containing protein -
  I6L84_RS08520 (I6L84_08520) - 1736441..1737310 (+) 870 WP_060552995.1 Rgg/GadR/MutR family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26275.27 Da        Isoelectric Point: 5.1861

>NTDB_id=580054 I6L84_RS08500 WP_045505796.1 1731966..1732655(-) (covR) [Streptococcus gordonii strain FDAARGOS 1454]
MAKRILLVENEKNLARFIMLELQKESYQVDLAETGQEGLALAKENDYDLLLLNNQFADGTAFAFAQQLSLLKPAAVIIVM
VSREEIADSAEEIQQFAVSYMVKPFIISDLVDKISAIFRGRDFIDQRCSQLKVPTAYRNLRVDLKNHTVYRGDEIIALTR
REYDLLVTLMSSNKVMSREQLLDRVWKYESASETNIVDVYIRYLRSKIDLPGQESYIKTVRGIGYSMQG

Nucleotide


Download         Length: 690 bp        

>NTDB_id=580054 I6L84_RS08500 WP_045505796.1 1731966..1732655(-) (covR) [Streptococcus gordonii strain FDAARGOS 1454]
ATGGCGAAGCGGATTTTATTAGTTGAAAATGAAAAGAATCTAGCACGATTTATCATGCTGGAATTACAAAAGGAAAGTTA
TCAAGTAGACCTAGCGGAAACAGGCCAAGAGGGACTAGCTCTAGCAAAGGAAAACGATTATGATTTACTTTTACTAAATA
ATCAGTTTGCTGATGGAACAGCCTTTGCCTTTGCTCAACAATTGAGTTTATTAAAACCTGCTGCAGTTATCATTGTAATG
GTGAGTCGAGAGGAAATTGCGGATTCGGCTGAAGAGATTCAGCAGTTTGCAGTTTCTTATATGGTAAAACCCTTTATTAT
CAGTGATTTGGTTGATAAGATATCCGCTATTTTTCGTGGGCGGGATTTTATCGATCAGAGATGTAGCCAGTTAAAAGTCC
CTACTGCTTATCGAAATCTGCGGGTTGATTTGAAAAATCATACGGTTTATCGAGGGGATGAAATTATTGCTTTGACGAGA
CGAGAGTACGATTTACTAGTGACTCTAATGAGCAGTAATAAGGTGATGAGTCGTGAGCAACTGTTAGACCGAGTGTGGAA
ATATGAAAGTGCATCTGAAACGAATATAGTGGATGTATATATTCGCTATCTCCGCAGTAAAATCGATCTTCCAGGTCAAG
AAAGTTATATTAAAACCGTTCGTGGAATTGGTTATTCCATGCAGGGTTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

51.77

98.69

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.737

99.563

0.445