Detailed information NTG0580016

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6L84_RS06225
• Genome accession: NZ_CP077224
• Coordinates: 1252573..1254813 (-)
• Length: 746 a.a.
• NCBI ID: WP_060554136.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain FDAARGOS 1454
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1247573..1259813

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L84_RS06195 (I6L84_06195)	-	1247846..1248343 (-)	498	WP_060554139.1	DUF1648 domain-containing protein	-
I6L84_RS06200 (I6L84_06200)	-	1248330..1248611 (-)	282	WP_012130660.1	autorepressor SdpR family transcription factor	-
I6L84_RS06205 (I6L84_06205)	-	1248589..1249377 (-)	789	WP_060554138.1	YhfC family intramembrane metalloprotease	-
I6L84_RS06210 (I6L84_06210)	-	1249582..1250655 (-)	1074	WP_081041949.1	serine hydrolase	-
I6L84_RS06215 (I6L84_06215)	-	1250767..1251372 (-)	606	WP_045503938.1	superoxide dismutase	-
I6L84_RS06220 (I6L84_06220)	holA	1251445..1252482 (-)	1038	WP_060554137.1	DNA polymerase III subunit delta	-
I6L84_RS06225 (I6L84_06225)	comEC/celB	1252573..1254813 (-)	2241	WP_060554136.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6L84_RS06230 (I6L84_06230)	comEA/celA/cilE	1254797..1255462 (-)	666	WP_060554135.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6L84_RS06235 (I6L84_06235)	-	1255559..1256086 (-)	528	WP_060554134.1	HXXEE domain-containing protein	-
I6L84_RS06240 (I6L84_06240)	-	1256125..1256865 (-)	741	WP_060554133.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
I6L84_RS06245 (I6L84_06245)	-	1256995..1259364 (+)	2370	WP_060554132.1	cation-translocating P-type ATPase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85062.93 Da
• Isoelectric Point: 9.8605

>NTDB_id=580016 I6L84_RS06225 WP_060554136.1 1252573..1254813(-) (comEC/celB) [Streptococcus gordonii strain FDAARGOS 1454]
MSQWIKKLPLSPIYLCFLLVWLYFAIYSGEKLAYLGVFLLIARLIWHYPRKKWLPTLAILACFAIFFYARRELTERTFQS
QPAPARQVLVLPDTIKVNGDSLSFRGRIAGRLYQLYYKLASPREKKTFQKLTDLVTLEIEAEFNLAEGQRNFSGFDYQAY
LKSQGIYRTVKVSGIISSRSSQSANPFDWLSVWRRKALVFIKSTFPSPMSHYMTGLLFGDLDIDFAEMNDLYSSLGIIHL
FALSGMQVGFFMDVFRKILLRIGLRMETVDWLQFPLSFIYAGLTGFSVSVVRSLVQKLLSQFGVRRLDNFAMTMLVLMLL
MPSFLLTTGGVLSCAYAFIITMLDFKDSSGFRKAVLESLSISLGILPILIYYFAEFQPWSILLTFLFSIVFDVFMLPLLS
LIFVLSPLFAITQVNIFFQWLEIVIRWVAGLSTRPIVLGQPNLTLLILLLLALALLYDFRKQKKIKAGLSLLAILLFFLS
KYPLQNEITVVDIGQGDSIFLRDIRGRTIVIDTGGRVEIGKKEAWQERVRKSNAETTLIPYLKSRGVDHLDQLVLTHTDT
DHMGDMLDLAKHFSIREIYVSKGSMTQSDFVGKLKKMKAKVHVVEVGDRLPIFDSALEVLYPLTQGDGGNDDSIVLYGEF
FRTKFLFTGDLEAPGEGQMVTAYPDLRVDVLKAGHHGSKGSSSPEFLEHIKPKLALISAGKNNRYQHPHQETLERFEKIQ
TKILRTDEQGAIRFKGWSSWKIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=580016 I6L84_RS06225 WP_060554136.1 1252573..1254813(-) (comEC/celB) [Streptococcus gordonii strain FDAARGOS 1454]
ATGTCACAGTGGATTAAAAAACTTCCCCTTTCACCAATCTATTTGTGCTTTCTTTTGGTTTGGCTTTACTTCGCTATTTA
TAGTGGGGAAAAGCTCGCTTATCTGGGAGTTTTTCTGCTTATAGCTCGCCTAATCTGGCATTATCCAAGAAAGAAATGGT
TGCCAACTTTGGCTATCCTAGCCTGTTTTGCTATCTTTTTTTATGCTAGACGCGAGTTGACGGAGCGAACCTTTCAGTCT
CAACCAGCTCCAGCAAGACAAGTCTTAGTTTTACCAGATACAATTAAAGTAAATGGAGATTCCCTGTCATTCCGTGGTAG
AATAGCTGGCAGACTCTATCAGCTCTACTACAAATTAGCAAGTCCAAGAGAGAAAAAAACTTTTCAAAAACTAACTGACT
TGGTCACTTTAGAGATAGAAGCGGAGTTCAATCTAGCAGAAGGACAGCGCAATTTCTCTGGCTTTGACTATCAGGCTTAT
TTAAAAAGTCAGGGAATCTATCGGACGGTTAAGGTCAGTGGGATTATCTCTAGTCGTTCTAGTCAGTCTGCTAATCCATT
TGATTGGCTGTCTGTTTGGCGTAGGAAGGCCTTGGTTTTCATTAAGTCTACTTTTCCAAGCCCGATGAGTCACTACATGA
CAGGACTCTTGTTTGGTGATTTAGATATTGATTTTGCAGAGATGAATGACTTGTACTCAAGTTTAGGAATTATCCATCTT
TTTGCTTTATCAGGAATGCAAGTTGGCTTTTTTATGGATGTCTTTCGAAAAATTCTTCTACGCATTGGCTTAAGAATGGA
AACAGTAGATTGGTTGCAATTCCCTTTGTCCTTTATTTATGCTGGTTTGACCGGATTTTCTGTGTCAGTAGTGAGAAGTT
TAGTGCAAAAGTTGTTGTCTCAATTTGGAGTGAGGCGCTTGGATAATTTTGCGATGACCATGCTGGTCTTAATGCTTCTT
ATGCCAAGCTTTCTCCTGACAACAGGCGGAGTCCTATCTTGCGCTTATGCCTTTATCATCACGATGTTGGACTTTAAAGA
TTCTAGTGGTTTTCGCAAAGCAGTGCTAGAGAGTTTAAGCATCTCGCTAGGTATTTTACCAATTCTTATCTATTATTTTG
CAGAATTCCAGCCTTGGTCTATCCTCTTGACCTTCCTTTTTTCAATCGTTTTTGATGTATTTATGTTGCCTCTCTTGAGT
CTAATTTTTGTCCTTTCGCCTTTGTTTGCCATCACTCAAGTTAATATCTTTTTCCAATGGCTGGAAATAGTTATACGTTG
GGTAGCTGGTCTGTCAACAAGGCCAATAGTTTTAGGTCAGCCCAATCTGACTTTGCTTATTCTTCTTCTACTAGCTTTAG
CCTTACTCTATGATTTTAGAAAACAAAAAAAGATTAAGGCTGGTCTGAGTCTGTTAGCAATCTTGCTATTTTTCCTAAGT
AAATATCCCTTGCAAAATGAAATCACAGTGGTTGATATTGGACAAGGAGATAGTATATTTCTGAGAGATATCAGAGGCCG
AACCATTGTAATTGATACAGGAGGACGGGTGGAGATTGGTAAAAAAGAGGCTTGGCAAGAGCGCGTGAGAAAAAGCAATG
CGGAAACGACCTTAATCCCTTATTTAAAAAGTCGAGGAGTGGATCACTTGGATCAATTAGTCCTGACTCACACAGATACA
GACCATATGGGAGATATGTTGGACTTAGCCAAGCATTTTTCTATCCGAGAAATTTATGTTTCCAAAGGAAGTATGACTCA
GTCTGATTTTGTAGGCAAGTTAAAGAAGATGAAAGCTAAAGTTCATGTAGTCGAGGTGGGAGATCGGCTTCCTATTTTTG
ATTCGGCTCTTGAAGTGCTCTACCCGCTTACTCAAGGAGATGGAGGTAATGATGATTCAATTGTCTTGTATGGTGAATTT
TTCCGGACCAAGTTTCTTTTCACAGGAGATTTAGAAGCTCCAGGTGAAGGTCAGATGGTGACAGCCTATCCAGATTTAAG
AGTAGATGTGCTCAAAGCTGGGCATCATGGTTCTAAAGGATCTTCTAGTCCAGAATTTCTAGAGCATATTAAGCCTAAGT
TGGCCTTGATTTCAGCTGGTAAAAACAATCGCTACCAGCATCCGCATCAGGAAACTTTAGAAAGATTTGAAAAAATCCAG
ACCAAGATTTTACGGACAGATGAGCAGGGTGCTATTCGATTTAAAGGATGGAGTTCTTGGAAGATAGAAACAGTTCGCTA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

• Domain of unknown function (DUF4131) (DUF4131) (35-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	58.768	100	0.588
comEC/celB	Streptococcus pneumoniae TIGR4	57.965	100	0.58
comEC/celB	Streptococcus mitis NCTC 12261	57.507	100	0.575
comEC/celB	Streptococcus pneumoniae Rx1	57.028	100	0.571
comEC/celB	Streptococcus pneumoniae D39	57.028	100	0.571
comEC/celB	Streptococcus pneumoniae R6	57.028	100	0.571
comEC	Lactococcus lactis subsp. cremoris KW2	50.538	99.732	0.504