Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   I6L84_RS03650 Genome accession   NZ_CP077224
Coordinates   728350..729579 (-) Length   409 a.a.
NCBI ID   WP_008808666.1    Uniprot ID   A0AAP2K4Q6
Organism   Streptococcus gordonii strain FDAARGOS 1454     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 725081..753081 728350..729579 within 0


Gene organization within MGE regions


Location: 725081..753081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L84_RS03630 (I6L84_03630) - 725081..725905 (-) 825 WP_060553604.1 alpha/beta hydrolase -
  I6L84_RS03635 (I6L84_03635) - 725999..726796 (-) 798 WP_060954898.1 formate/nitrite transporter family protein -
  I6L84_RS03640 (I6L84_03640) - 726924..727613 (-) 690 WP_012000547.1 glucosaminidase domain-containing protein -
  I6L84_RS03645 (I6L84_03645) yihA 727747..728340 (-) 594 WP_048779982.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  I6L84_RS03650 (I6L84_03650) clpX 728350..729579 (-) 1230 WP_008808666.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  I6L84_RS03655 (I6L84_03655) - 729788..730300 (-) 513 WP_060553602.1 dihydrofolate reductase -
  I6L84_RS03660 (I6L84_03660) - 730446..730946 (-) 501 WP_060553601.1 hypothetical protein -
  I6L84_RS03665 (I6L84_03665) - 731077..731916 (-) 840 WP_060553600.1 thymidylate synthase -
  I6L84_RS03670 (I6L84_03670) - 732015..732974 (-) 960 WP_060553599.1 ROK family glucokinase -
  I6L84_RS03675 (I6L84_03675) - 733149..733994 (-) 846 WP_060553598.1 alpha/beta hydrolase -
  I6L84_RS03680 (I6L84_03680) - 734062..735274 (-) 1213 Protein_695 IS3 family transposase -
  I6L84_RS03685 (I6L84_03685) - 735389..743482 (-) 8094 WP_111705895.1 GEVED domain-containing protein -
  I6L84_RS03690 (I6L84_03690) - 743663..744265 (-) 603 WP_046165585.1 lysozyme family protein -
  I6L84_RS03695 (I6L84_03695) - 744265..745239 (-) 975 WP_060553589.1 nucleoid-associated protein -
  I6L84_RS03700 (I6L84_03700) glyA 745241..746503 (-) 1263 WP_045503008.1 serine hydroxymethyltransferase -
  I6L84_RS03705 (I6L84_03705) - 746551..747141 (-) 591 WP_060553588.1 L-threonylcarbamoyladenylate synthase -
  I6L84_RS03710 (I6L84_03710) prmC 747134..747964 (-) 831 WP_060553587.1 peptide chain release factor N(5)-glutamine methyltransferase -
  I6L84_RS03715 (I6L84_03715) prfA 747964..749043 (-) 1080 WP_060553586.1 peptide chain release factor 1 -
  I6L84_RS03720 (I6L84_03720) - 749076..749651 (-) 576 WP_045503019.1 thymidine kinase -
  I6L84_RS03725 (I6L84_03725) - 749773..749955 (+) 183 WP_060553585.1 4-oxalocrotonate tautomerase -
  I6L84_RS03730 (I6L84_03730) - 750069..751334 (-) 1266 WP_037622361.1 nucleobase:cation symporter-2 family protein -
  I6L84_RS03735 (I6L84_03735) - 751336..751917 (-) 582 WP_008808652.1 xanthine phosphoribosyltransferase -
  I6L84_RS03740 (I6L84_03740) guaC 752098..753081 (-) 984 WP_008808651.1 GMP reductase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45650.21 Da        Isoelectric Point: 4.4870

>NTDB_id=580010 I6L84_RS03650 WP_008808666.1 728350..729579(-) (clpX) [Streptococcus gordonii strain FDAARGOS 1454]
MPTNRNEEMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLHILNHYVIGQER
AKRALAVAVYNHYKRINFHDSREEDDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENESYMQAIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LREPKNALVKQYQALLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSKENVKLVRITKEAVDG
TDKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=580010 I6L84_RS03650 WP_008808666.1 728350..729579(-) (clpX) [Streptococcus gordonii strain FDAARGOS 1454]
ATGCCTACCAATCGTAATGAAGAGATGATGGTATATTGTTCATTTTGTGGGAAGAACCAAGATGAAGTTCAAAAGATTAT
TGCAGGTAATAACGCTTTTATTTGTAATGAGTGTGTAGAATTAGCGCAAGAAATTATCCGTGAAGAATTGGCCGAAGAAG
TCTTAGCTGACTTGTCAGAGGTTCCAAAACCTCAAGAATTATTGCATATTCTAAACCATTATGTCATCGGCCAAGAGCGT
GCTAAAAGAGCGCTAGCTGTAGCGGTATATAATCACTACAAGCGTATTAATTTTCATGACAGTCGCGAAGAAGACGATGT
TGAATTACAAAAATCAAATATTTTAATGATCGGTCCAACGGGTTCTGGAAAAACTTTTCTTGCTCAAACCTTGGCTAGAA
GTTTAAATGTGCCATTTGCGATTGCTGATGCGACAGCATTAACAGAGGCTGGTTATGTCGGAGAAGATGTAGAAAATATT
CTTTTAAAACTTTTACAGGCGGCTGATTTCAATATTGAACGTGCAGAACGCGGAATTATCTACGTTGATGAGATTGATAA
GATCGCTAAAAAAAGTGAAAATGTTTCTATCACGCGCGATGTATCAGGTGAAGGAGTACAGCAAGCACTCTTAAAAATTA
TCGAGGGTACTGTAGCAAGTGTTCCGCCTCAAGGAGGTCGCAAGCATCCGCAGCAAGAAATGATTCAAGTTGATACCAAA
AATATTCTTTTCATCGTTGGTGGTGCCTTTGATGGAATTGAAGAAATTGTTAAACAACGTTTGGGCGAGAAAATTATTGG
TTTTGGTCAAAATAACAAAGCTATTGATGAAAACGAGTCCTACATGCAGGCTATTATTGCCGAAGATATTCAAAAATTTG
GAATTATCCCTGAATTAATTGGTCGTTTGCCTGTTTTTGCTGCTCTGGAACAACTGACTGTAGATGACTTGGTTCGTATT
CTTCGTGAACCTAAGAATGCTTTGGTTAAACAATACCAAGCTCTCTTGTCTTATGATGATGTTAAACTAGAGTTTGATGA
TGATGCTTTACAGGAAATCGCGAACAAGGCCATTGAGCGCAAAACTGGTGCTCGCGGTCTACGTTCTATCATCGAAGAAA
CCATGATGGATGTTATGTTTGAAGTTCCAAGTAAAGAAAATGTGAAACTTGTCAGAATTACGAAGGAAGCCGTTGATGGT
ACGGATAAACCAATTTTAGAGACTGCTTGA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

85.575

100

0.856
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.105

98.044

0.57