Detailed information NTG0057954

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: SPN994039_RS08930
• Genome accession: NC_021005
• Coordinates: 1670458..1671525 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159555.1
• Uniprot ID: A0A0I8P776
• Organism: Streptococcus pneumoniae SPN994039
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1665458..1676525

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN994039_RS08905 (SPN994039_16500)	treR	1667246..1667956 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
SPN994039_RS11855 (SPN994039_16510)	-	1668111..1669446 (+)	1336	Protein_1719	ISL3 family transposase	-
SPN994039_RS08925 (SPN994039_16520)	amiF	1669521..1670447 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
SPN994039_RS08930 (SPN994039_16530)	amiE	1670458..1671525 (-)	1068	WP_000159555.1	ABC transporter ATP-binding protein	Regulator
SPN994039_RS08935 (SPN994039_16540)	amiD	1671534..1672460 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
SPN994039_RS08940 (SPN994039_16550)	amiC	1672460..1673956 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
SPN994039_RS08945 (SPN994039_16560)	amiA3	1674023..1676002 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39489.14 Da
• Isoelectric Point: 5.0389

>NTDB_id=57954 SPN994039_RS08930 WP_000159555.1 1670458..1671525(-) (amiE) [Streptococcus pneumoniae SPN994039]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=57954 SPN994039_RS08930 WP_000159555.1 1670458..1671525(-) (amiE) [Streptococcus pneumoniae SPN994039]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCTT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAAAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A0I8P776

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541