Detailed information NTG0579373

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: KSG66_RS16835
• Genome accession: NZ_CP077106
• Coordinates: 3408209..3409372 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain DW-7
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3403209..3414372

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KSG66_RS16805 (KSG66_16690)	-	3403473..3403892 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
KSG66_RS16810 (KSG66_16695)	comFC	3403966..3404655 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
KSG66_RS16815 (KSG66_16700)	-	3404661..3404945 (-)	285	WP_003151389.1	competence protein ComFB	-
KSG66_RS16820 (KSG66_16705)	comFA	3405003..3406388 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
KSG66_RS16825 (KSG66_16710)	-	3406497..3407345 (-)	849	WP_032876160.1	DegV family protein	-
KSG66_RS16830 (KSG66_16715)	degU	3407443..3408132 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
KSG66_RS16835 (KSG66_16720)	degS	3408209..3409372 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
KSG66_RS16840 (KSG66_16725)	-	3409595..3410242 (+)	648	WP_007614107.1	YigZ family protein	-
KSG66_RS16845 (KSG66_16730)	-	3410247..3411428 (+)	1182	WP_032876157.1	LCP family protein	-
KSG66_RS16850 (KSG66_16735)	-	3411527..3412603 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
KSG66_RS16855 (KSG66_16740)	-	3412736..3413932 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=579373 KSG66_RS16835 WP_007407484.1 3408209..3409372(-) (degS) [Bacillus velezensis strain DW-7]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=579373 KSG66_RS16835 WP_007407484.1 3408209..3409372(-) (degS) [Bacillus velezensis strain DW-7]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951