Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SPN032672_RS08190 Genome accession   NC_021003
Coordinates   1529349..1530038 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae SPN032672     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1524349..1535038
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN032672_RS08165 gpsB 1524458..1524787 (+) 330 WP_000146522.1 cell division regulator GpsB -
  SPN032672_RS08175 - 1525273..1526430 (+) 1158 WP_000711408.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  SPN032672_RS08180 mapZ 1526443..1527837 (+) 1395 WP_000039278.1 cell division site-positioning protein MapZ -
  SPN032672_RS08185 gndA 1527913..1529337 (+) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  SPN032672_RS08190 covR 1529349..1530038 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  SPN032672_RS08195 cbpC 1530136..1531092 (+) 957 WP_000771100.1 choline-binding protein CbpC -
  SPN032672_RS08200 - 1531210..1532442 (-) 1233 WP_000765667.1 MFS transporter -
  SPN032672_RS08205 - 1532485..1533072 (-) 588 WP_001818729.1 lanthionine synthetase LanC family protein -
  SPN032672_RS12220 - 1532972..1533308 (-) 337 Protein_1530 lanthionine synthetase LanC family protein -
  SPN032672_RS14005 - 1533970..1534299 (+) 330 WP_000196971.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=57897 SPN032672_RS08190 WP_000518008.1 1529349..1530038(+) (covR) [Streptococcus pneumoniae SPN032672]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=57897 SPN032672_RS08190 WP_000518008.1 1529349..1530038(+) (covR) [Streptococcus pneumoniae SPN032672]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment