Detailed information    

insolico Bioinformatically predicted

Overview

Name   degS   Type   Regulator
Locus tag   KP952_RS18650 Genome accession   NZ_CP076731
Coordinates   3507850..3509007 (-) Length   385 a.a.
NCBI ID   WP_003227983.1    Uniprot ID   A0A199WDV9
Organism   Bacillus subtilis subsp. subtilis strain Miz-8     
Function   phosphorylation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3502850..3514007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KP952_RS18620 (KP952_18620) yvyF 3503103..3503522 (-) 420 WP_038429728.1 TIGR03826 family flagellar region protein -
  KP952_RS18625 (KP952_18625) comFC 3503595..3504317 (-) 723 WP_014481051.1 comF operon protein ComFC Machinery gene
  KP952_RS18630 (KP952_18630) comFB 3504281..3504577 (-) 297 WP_003227989.1 late competence protein ComFB -
  KP952_RS18635 (KP952_18635) comFA 3504637..3506028 (-) 1392 WP_014481052.1 ATP-dependent helicase ComFA Machinery gene
  KP952_RS18640 (KP952_18640) fakBA 3506135..3506980 (-) 846 WP_014481053.1 DegV family protein -
  KP952_RS18645 (KP952_18645) degU 3507078..3507767 (-) 690 WP_014481054.1 two-component system response regulator DegU Regulator
  KP952_RS18650 (KP952_18650) degS 3507850..3509007 (-) 1158 WP_003227983.1 two-component sensor histidine kinase DegS Regulator
  KP952_RS18655 (KP952_18655) - 3509224..3509877 (+) 654 WP_014481055.1 YigZ family protein -
  KP952_RS18660 (KP952_18660) - 3509877..3510869 (+) 993 WP_014481056.1 LCP family protein -
  KP952_RS18665 (KP952_18665) - 3511467..3511931 (+) 465 WP_225910700.1 hypothetical protein -
  KP952_RS18670 (KP952_18670) - 3511980..3512435 (+) 456 WP_014481057.1 hypothetical protein -
  KP952_RS18675 (KP952_18675) - 3512486..3512938 (+) 453 WP_014481058.1 hypothetical protein -
  KP952_RS18680 (KP952_18680) - 3513014..3513793 (+) 780 WP_014481059.1 hypothetical protein -

Sequence

Protein


Download         Length: 385 a.a.        Molecular weight: 44957.76 Da        Isoelectric Point: 6.2957

>NTDB_id=577790 KP952_RS18650 WP_003227983.1 3507850..3509007(-) (degS) [Bacillus subtilis subsp. subtilis strain Miz-8]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide


Download         Length: 1158 bp        

>NTDB_id=577790 KP952_RS18650 WP_003227983.1 3507850..3509007(-) (degS) [Bacillus subtilis subsp. subtilis strain Miz-8]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAAGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGGATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

Histidine kinase (HisKA_3)

(180-248)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(291-384)

Sensor protein DegS (DegS)

(12-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A199WDV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degS Bacillus subtilis subsp. subtilis str. 168

100

100

1