Detailed information NTG0577464

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: KRG72_RS05255
• Genome accession: NZ_CP076703
• Coordinates: 1047739..1048968 (-)
• Length: 409 a.a.
• NCBI ID: WP_074560306.1
• Uniprot ID: A0A1H0YH95
• Organism: Streptococcus equinus strain S1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1042739..1053968

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KRG72_RS05235 (KRG72_05240)	-	1043967..1044635 (+)	669	WP_074561098.1	YoaK family protein	-
KRG72_RS05240 (KRG72_05245)	mmuM	1044667..1045611 (-)	945	WP_258250144.1	homocysteine S-methyltransferase	-
KRG72_RS05245 (KRG72_05250)	-	1045622..1046998 (-)	1377	WP_166044283.1	amino acid permease	-
KRG72_RS05250 (KRG72_05255)	yihA	1047135..1047728 (-)	594	WP_074560304.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
KRG72_RS05255 (KRG72_05260)	clpX	1047739..1048968 (-)	1230	WP_074560306.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
KRG72_RS05260 (KRG72_05265)	-	1049197..1049691 (-)	495	WP_258250145.1	dihydrofolate reductase	-
KRG72_RS05265 (KRG72_05270)	-	1049774..1050613 (-)	840	WP_258250146.1	thymidylate synthase	-
KRG72_RS05270 (KRG72_05275)	-	1050942..1052117 (+)	1176	WP_074602113.1	hydroxymethylglutaryl-CoA synthase	-
KRG72_RS05275 (KRG72_05280)	-	1052107..1053378 (+)	1272	WP_258250147.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45254.78 Da
• Isoelectric Point: 4.4880

>NTDB_id=577464 KRG72_RS05255 WP_074560306.1 1047739..1048968(-) (clpX) [Streptococcus equinus strain S1]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQER
AKRALAVAVYNHYKRVSFAESRDEEDVELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDEDASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTTDDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDEDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSREEVTKVRITKDAVEG
KDKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=577464 KRG72_RS05255 WP_074560306.1 1047739..1048968(-) (clpX) [Streptococcus equinus strain S1]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTTTGTGGAAAAAGCCAAGACGAAGTAAAAAAAATCAT
TGCCGGAAATAACGTATTTATCTGTAATGAATGTGTGGCTTTATCCCAAGAGATTATTAAAGAGGAGTTAGCAGAAGAAG
TTCTCGCAGATTTGGCTGAAGTTCCAAAACCAAAAGAATTATTAGCAACCCTCGATGAATATGTTGTCGGTCAAGAACGC
GCTAAACGTGCCCTCGCAGTGGCTGTATATAACCACTACAAACGTGTTTCTTTTGCCGAAAGTCGTGATGAAGAAGATGT
TGAATTACAAAAATCTAACATCCTATTAATCGGACCAACTGGTTCAGGGAAAACTTTCCTTGCCCAAACTTTGGCGAAAA
GTTTAAACGTTCCATTTGCGATTGCTGACGCGACATCATTGACAGAAGCAGGATATGTTGGTGAGGACGTTGAAAACATC
CTTTTGAAACTTATTCAAGCGGCTGATTTTAATATTGAACGTGCAGAACGTGGTATCATCTACGTGGATGAAATTGATAA
AATTGCCAAAAAAGGCGAAAATGTCTCAATCACTCGTGATGTTTCAGGTGAAGGTGTTCAACAAGCTCTCCTTAAAATTA
TCGAAGGAACAGTAGCAAGCGTTCCACCACAAGGTGGTCGTAAACACCCTAACCAAGAAATGATTCAAATCAATACTAAG
AACATTCTTTTCATCGTTGGTGGTGCTTTTGACGGTATTGAAGATATTGTTAAACAACGTCTCGGTGAAAAAGTTATTGG
TTTTGGACAAAATAACCGTAAGATTGATGAAGATGCTTCTTACATGCAAGAAATCATCTCCGAAGATATTCAAAAATTTG
GTTTGATTCCTGAATTTATCGGGCGCTTGCCAGTCGTTGCTGCGCTTGAACAATTGACAACAGATGATTTGGTACGTATC
TTAACTGAACCTCGTAATGCTTTGGTTAAACAATACCAAACACTTCTATCATATGATGGTGTTGAGTTGGAATTTGATGA
AGACGCCCTTCAAGCTATTGCTAATAAGGCTATCGAACGTAAGACAGGTGCACGTGGACTTCGTTCAATCATTGAAGAAA
CAATGATGGATATCATGTTTGAAATTCCAAGTCGTGAAGAAGTCACTAAAGTCCGCATCACAAAAGATGCTGTTGAAGGC
AAAGATAAACCAATTTTAGAGATTGCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

3D structure

• AlphaFold DB: A0A1H0YH95

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.242	100	0.892
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.853	98.044	0.577