Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   KRG72_RS02400 Genome accession   NZ_CP076703
Coordinates   454012..455310 (+) Length   432 a.a.
NCBI ID   WP_258255721.1    Uniprot ID   -
Organism   Streptococcus equinus strain S1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 449012..460310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS02375 (KRG72_02375) - 449678..450322 (+) 645 WP_006531177.1 response regulator transcription factor -
  KRG72_RS02380 (KRG72_02380) - 450446..451846 (+) 1401 WP_081341909.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  KRG72_RS02385 (KRG72_02385) - 451846..452202 (+) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -
  KRG72_RS02390 (KRG72_02390) cysK 452302..453231 (-) 930 WP_074561282.1 cysteine synthase A -
  KRG72_RS02395 (KRG72_02395) - 453331..453957 (-) 627 WP_258255720.1 YigZ family protein -
  KRG72_RS02400 (KRG72_02400) comFA/cflA 454012..455310 (+) 1299 WP_258255721.1 DEAD/DEAH box helicase Machinery gene
  KRG72_RS02405 (KRG72_02405) - 455310..455972 (+) 663 WP_258255722.1 ComF family protein -
  KRG72_RS02410 (KRG72_02410) hpf 456049..456597 (+) 549 WP_039695883.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49098.32 Da        Isoelectric Point: 9.8279

>NTDB_id=577452 KRG72_RS02400 WP_258255721.1 454012..455310(+) (comFA/cflA) [Streptococcus equinus strain S1]
MTELNDYYGRIFTESQLTDDLKKEAKVLPSVKKEKGQMICNRCGSVMEANQMLQTGRIYCRECLVFGRNTSDSNLYYFPQ
KPFTKTQSLNWQGKLTPYQDEVSKGILKGITEKQDLLIHAVTGAGKTEMIYQSLAKVIDNGGSVCLASPRIDVCLELYKR
LSRDFSCPITLLHGDSEPYKRSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYHAVNQSLKDDGVKLFLTATST
DELDKKVKKGELTKLHLARRFHANPLVVPKMVWLSKVLISMKKKKLPPKLISLFKKQRQSQFPLLIFFPNIEQGREFTSI
LQTTFPDERIGFVSSKTENRLELVEEFRQGKLTILVTTTILERGVTFPCVDVFVLLANHKLYSKSALVQISGRVGRAAER
PTGELLFLHDGVTKAMKKAISEIKEMNHKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=577452 KRG72_RS02400 WP_258255721.1 454012..455310(+) (comFA/cflA) [Streptococcus equinus strain S1]
ATGACAGAGTTGAATGATTACTATGGAAGAATTTTTACAGAAAGTCAATTAACAGATGACTTGAAAAAGGAAGCAAAAGT
CCTTCCTTCGGTTAAAAAGGAAAAAGGTCAAATGATTTGCAATCGCTGTGGAAGTGTAATGGAAGCAAATCAAATGTTGC
AAACTGGTCGCATTTATTGTAGAGAGTGTTTAGTTTTTGGGAGAAATACTAGTGATTCTAATCTTTATTATTTCCCTCAG
AAGCCTTTTACAAAGACTCAGTCTTTAAATTGGCAAGGAAAACTAACTCCTTATCAAGATGAAGTTTCTAAAGGCATACT
TAAAGGTATTACAGAAAAACAAGATTTATTGATTCACGCTGTGACTGGTGCTGGTAAAACTGAAATGATTTATCAATCTT
TAGCCAAAGTTATTGATAATGGTGGAAGTGTCTGCTTAGCGAGTCCACGGATTGATGTTTGTTTAGAACTTTATAAACGT
TTATCACGGGATTTTTCTTGCCCGATTACGCTTTTACACGGTGATTCTGAGCCGTATAAACGTTCTCCACTGGTAATTGC
AACGACCCATCAACTTTTAAAATTTTACCGAGCATTTGATTTATTAATCATCGACGAAGTTGATGCCTTTCCCTTTGTTG
ACAATAAAATGCTTTATCACGCTGTCAATCAATCGCTAAAAGATGATGGCGTTAAACTCTTTCTAACAGCGACTTCTACA
GATGAATTAGATAAAAAAGTCAAAAAAGGAGAGTTGACAAAATTGCATTTAGCAAGACGTTTTCACGCCAATCCCCTGGT
GGTTCCAAAAATGGTTTGGTTAAGCAAAGTGCTAATCTCAATGAAAAAGAAAAAACTTCCTCCTAAACTAATTTCTCTTT
TTAAAAAACAAAGGCAAAGTCAATTTCCGCTTCTCATATTTTTCCCAAATATTGAACAAGGTAGAGAATTTACAAGTATC
TTACAAACCACTTTTCCAGATGAAAGGATAGGATTTGTATCAAGTAAAACTGAAAATCGTTTGGAATTGGTAGAAGAATT
TAGACAAGGAAAATTAACCATACTAGTGACGACAACCATTCTAGAACGTGGGGTAACCTTTCCTTGTGTCGATGTTTTTG
TTCTACTTGCAAATCATAAATTGTACAGCAAAAGTGCACTTGTTCAGATTTCTGGTCGAGTTGGACGAGCAGCCGAGAGA
CCGACAGGAGAGCTATTGTTCTTGCATGATGGCGTAACAAAAGCTATGAAAAAGGCTATTTCTGAAATAAAAGAAATGAA
TCATAAAGGAGGATTTTAA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(96-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

61.358

98.843

0.606
  comFA/cflA Streptococcus pneumoniae D39

61.358

98.843

0.606
  comFA/cflA Streptococcus pneumoniae R6

61.358

98.843

0.606
  comFA/cflA Streptococcus pneumoniae TIGR4

61.358

98.843

0.606
  comFA/cflA Streptococcus mitis NCTC 12261

61.124

98.843

0.604
  comFA/cflA Streptococcus mitis SK321

60.656

98.843

0.6
  comFA Lactococcus lactis subsp. cremoris KW2

49.764

98.148

0.488
  comFA Latilactobacillus sakei subsp. sakei 23K

38.161

100

0.384