Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MQV61_RS10325 Genome accession   NZ_CP094339
Coordinates   2160731..2161387 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain W224N     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2155731..2166387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MQV61_RS10295 dcyD 2156610..2157596 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  MQV61_RS10300 tcyL 2157611..2158279 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  MQV61_RS10305 tcyN 2158276..2159028 (+) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MQV61_RS10310 sdiA 2159258..2159980 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  MQV61_RS10315 yecF 2160048..2160272 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  MQV61_RS10320 yecU 2160259..2160435 (-) 177 WP_001307856.1 protein YecU -
  MQV61_RS10325 letA 2160731..2161387 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MQV61_RS10330 uvrC 2161384..2163216 (+) 1833 WP_001283418.1 excinuclease ABC subunit UvrC Machinery gene
  MQV61_RS10335 pgsA 2163273..2163821 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MQV61_RS10355 yecA 2164471..2165136 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=577442 MQV61_RS10325 WP_000611328.1 2160731..2161387(+) (letA) [Escherichia coli strain W224N]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=577442 MQV61_RS10325 WP_000611328.1 2160731..2161387(+) (letA) [Escherichia coli strain W224N]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482