Detailed information NTG0577296

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: LUW75_RS09950
• Genome accession: NZ_CP094264
• Coordinates: 2198713..2199834 (+)
• Length: 373 a.a.
• NCBI ID: WP_168438873.1
• Uniprot ID: A0AA44DD21
• Organism: Streptomyces sp. MRC013
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2193713..2204834

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LUW75_RS09935 (LUW75_09935)	-	2194350..2195093 (+)	744	WP_250337613.1	hypothetical protein	-
LUW75_RS09940 (LUW75_09940)	-	2195101..2196783 (-)	1683	WP_250335282.1	hypothetical protein	-
LUW75_RS09945 (LUW75_09945)	radA/sms	2197172..2198572 (+)	1401	WP_250335283.1	DNA repair protein RadA	Machinery gene
LUW75_RS09950 (LUW75_09950)	disA	2198713..2199834 (+)	1122	WP_168438873.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
LUW75_RS09955 (LUW75_09955)	-	2199865..2200709 (-)	845	Protein_1974	hypothetical protein	-
LUW75_RS09960 (LUW75_09960)	-	2200878..2201603 (+)	726	WP_250335284.1	phosphatase PAP2 family protein	-
LUW75_RS09965 (LUW75_09965)	-	2201672..2202585 (+)	914	Protein_1976	A/G-specific adenine glycosylase	-
LUW75_RS09970 (LUW75_09970)	-	2202793..2203335 (+)	543	WP_250335285.1	SigE family RNA polymerase sigma factor	-
LUW75_RS09975 (LUW75_09975)	-	2203367..2204035 (+)	669	WP_250335286.1	hypothetical protein	-
LUW75_RS09980 (LUW75_09980)	cseB	2204055..2204747 (+)	693	WP_250335287.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 40187.03 Da
• Isoelectric Point: 4.9406

>NTDB_id=577296 LUW75_RS09950 WP_168438873.1 2198713..2199834(+) (disA) [Streptomyces sp. MRC013]
MAANDRATPGKSGGGSGNEALMRASLSAVAPGTALRDGLERILRGNTGGLIVLGMDRTVESMCTGGFVLDVEFTATRLRE
LCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSRQCGFPVISVSQSMRLIALYVDGERRVLEESAAI
LSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIAG
VEPERELVVRDYVPEPTAKRSRTVAEALTELDALSHAELLELPTVARALGYSGSPETLDSAVSPRGYRLLAKVPRLPGAI
IERLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1122 bp

>NTDB_id=577296 LUW75_RS09950 WP_168438873.1 2198713..2199834(+) (disA) [Streptomyces sp. MRC013]
GTGGCAGCCAACGACCGGGCAACACCCGGAAAGTCGGGCGGAGGCTCCGGCAACGAAGCGCTGATGCGCGCGTCCCTCAG
CGCGGTCGCCCCCGGCACGGCGCTGAGGGACGGACTGGAGCGCATCCTCCGCGGCAACACGGGCGGTCTGATCGTCCTCG
GCATGGACAGGACCGTCGAGTCGATGTGCACCGGCGGTTTCGTACTGGACGTGGAGTTCACCGCGACCCGCCTGCGCGAG
CTGTGCAAGCTCGACGGCGCGCTCATCCTCGACAAGGACATCACCAAGATCCTCCGCGCCGGCGTCCAGCTGGTCCCCGA
CGCGTCGATCCCGACCGAGGAGACCGGCACGCGGCACCGCACGGCGGACCGGGTGTCCAGGCAGTGCGGCTTCCCGGTGA
TCTCCGTGTCGCAGTCGATGCGTCTGATCGCCCTGTACGTGGACGGCGAGCGCCGCGTCCTGGAGGAGTCCGCCGCGATC
CTCTCCCGCGCCAACCAGGCCCTCGCCACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTGGCCGGGACGCTCTCCGC
GCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTGACGGCCGTGGCACAGCGCCTGGAGATGGTCCGCCGGATCGCCA
CGGAGATCGCGGAGTACGTCGTCGAGCTGGGTACGGACGGCCGCCTCCTCGCCCTCCAGCTGGACGAGCTGATCGCGGGC
GTCGAGCCGGAGCGGGAGCTGGTGGTGCGGGACTACGTGCCCGAGCCGACCGCGAAGCGGTCCCGTACGGTCGCGGAGGC
GCTGACGGAGCTGGACGCGCTGTCCCACGCCGAGCTGCTGGAGCTGCCGACGGTGGCCCGGGCGCTCGGCTACAGCGGTT
CGCCGGAGACGCTGGACTCGGCGGTCTCGCCGCGCGGCTACCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGCGCCATC
ATCGAGCGGCTGGTGGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCGGCGAGCGTCGACGACCTGCAGGCCGTCGACGG
CGTCGGCGAGGCGCGCGCCCGCAGCGTCCGGGAGGGCCTGTCTCGGCTCGCCGAGTCGTCGATCCTGGAGCGGTACGTCT
GA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (323-358)

• DisA bacterial checkpoint controller linker region (DisA-linker) (154-296)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (37-150)

3D structure

• AlphaFold DB: A0AA44DD21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.983	96.783	0.445