Detailed information NTG0576777

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: MPG18_RS00840
• Genome accession: NZ_CP094165
• Coordinates: 175057..177633 (+)
• Length: 858 a.a.
• NCBI ID: WP_245078135.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain Hpfe0011
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 170057..182633

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MPG18_RS00805 (MPG18_00805)	-	171808..172068 (+)	261	WP_213209156.1	type VII secretion protein	-
MPG18_RS00810 (MPG18_00810)	-	172078..172901 (+)	824	Protein_156	5-amino-6-(5-phosphoribosylamino)uracil reductase	-
MPG18_RS00815 (MPG18_00815)	-	172884..173672 (+)	789	WP_245078677.1	integrase	-
MPG18_RS00820 (MPG18_00820)	-	173776..174255 (+)	480	WP_245078131.1	hypothetical protein	-
MPG18_RS00825 (MPG18_00825)	comB2	174252..174536 (+)	285	WP_000736478.1	TrbC/VirB2 family protein	Machinery gene
MPG18_RS00830 (MPG18_00830)	comB3	174547..174810 (+)	264	WP_001177712.1	hypothetical protein	Machinery gene
MPG18_RS00835 (MPG18_00835)	-	174821..175057 (+)	237	WP_245078133.1	hypothetical protein	-
MPG18_RS00840 (MPG18_00840)	comB4	175057..177633 (+)	2577	WP_245078135.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
MPG18_RS00845 (MPG18_00845)	-	177635..177769 (+)	135	WP_021301032.1	hypothetical protein	-
MPG18_RS00850 (MPG18_00850)	-	177762..178934 (+)	1173	WP_245078137.1	VirB8/TrbF family protein	-
MPG18_RS00855 (MPG18_00855)	-	178931..180601 (+)	1671	WP_245078139.1	TrbG/VirB9 family P-type conjugative transfer protein	-
MPG18_RS00860 (MPG18_00860)	comB10	180598..181800 (+)	1203	WP_180671645.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98813.81 Da
• Isoelectric Point: 8.6382

>NTDB_id=576777 MPG18_RS00840 WP_245078135.1 175057..177633(+) (comB4) [Helicobacter pylori strain Hpfe0011]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSKKDKKNKFKKKTTFSTTSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKLSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSPSNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALRINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNIV
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLA

Nucleotide

• Length: 2577 bp

>NTDB_id=576777 MPG18_RS00840 WP_245078135.1 175057..177633(+) (comB4) [Helicobacter pylori strain Hpfe0011]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGTTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
TCCATACGCAAAAGCCATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGCACCACAAGTAAAAGAGCCTTACTCATTCAAACAATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAGTTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACTCTCTTATTTT
TCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGTGCTTTAAAATACCCCAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATGAAGGCG
AAAGCTTTCATATCAATCCTTTTTCATTAGAGGATAGCCCAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGACAGCATTTTACATAATGATGATGACGCTGG
GCTTTTAGCCTATTATGTCTTTCATAAGATGATTGATAGAGCCTTGAGAATCAATCGTGGGTTTTTGTGTTTTATTGATG
AGTTTAAATCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTGATTGTTTTAGCCTTACAAGACATTAACCAACTTAGTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTGTA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAACACTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTGCCTAA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-504)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.849	98.019	0.459