Detailed information NTG0576477

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: MPG81_RS07655
• Genome accession: NZ_CP094151
• Coordinates: 1599467..1602040 (+)
• Length: 857 a.a.
• NCBI ID: WP_245088405.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain Hpfe019
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1594467..1607040

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MPG81_RS07625 (MPG81_07625)	-	1595134..1597851 (-)	2718	Protein_1490	type I restriction endonuclease subunit R	-
MPG81_RS07630 (MPG81_07630)	-	1597787..1598122 (+)	336	Protein_1491	integrase	-
MPG81_RS07635 (MPG81_07635)	-	1598226..1598705 (+)	480	WP_245087010.1	hypothetical protein	-
MPG81_RS07640 (MPG81_07640)	comB2	1598702..1598986 (+)	285	WP_245087012.1	TrbC/VirB2 family protein	Machinery gene
MPG81_RS07645 (MPG81_07645)	comB3	1598997..1599260 (+)	264	WP_060760559.1	hypothetical protein	Machinery gene
MPG81_RS07650 (MPG81_07650)	-	1599271..1599570 (+)	300	WP_245087014.1	hypothetical protein	-
MPG81_RS07655 (MPG81_07655)	comB4	1599467..1602040 (+)	2574	WP_245088405.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
MPG81_RS07660 (MPG81_07660)	-	1602037..1602171 (+)	135	WP_245087016.1	type IV secretion system protein VirB7	-
MPG81_RS07665 (MPG81_07665)	-	1602164..1603327 (+)	1164	WP_245087018.1	VirB8/TrbF family protein	-
MPG81_RS07670 (MPG81_07670)	-	1603330..1604999 (+)	1670	Protein_1499	TrbG/VirB9 family P-type conjugative transfer protein	-
MPG81_RS07675 (MPG81_07675)	comB10	1604996..1606195 (+)	1200	WP_245087020.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 98589.73 Da
• Isoelectric Point: 8.6445

>NTDB_id=576477 MPG81_RS07655 WP_245088405.1 1599467..1602040(+) (comB4) [Helicobacter pylori strain Hpfe019]
MILIPLKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLNTIS
KDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEESSKE
NKQENENSSNETHSNTSSNKDKKNKFKKKITFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKYIAF
NPKLKRLIDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESLNFL
KTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYFSFF
PNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGNMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGHTMI
IGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSASNRAFLLHFYAQMAKV
DSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEDYLKSSLFSSRMD
SLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALRINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANGVIV
LALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNIIDVS
LSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLCPT

Nucleotide

• Length: 2574 bp

>NTDB_id=576477 MPG81_RS07655 WP_245088405.1 1599467..1602040(+) (comB4) [Helicobacter pylori strain Hpfe019]
ATAATTCTAATCCCCCTAAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTATGACAGAGGA
ATGCAATATTTTAGGCTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGTCTTTACAAG
GACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAACACCATTAGT
AAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAACCCATACGC
AAAAGCTATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCATTACTTCTA
ATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGCTCTAAAGAG
AATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAACAAAGACAAGAAAAACAAGTTCAA
AAAAAAGATAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACGCATTAAGGG
AGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATATATCGCCTTT
AATCCTAAATTAAAGCGACTAATCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCATCATTGAATT
TCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCCCCATTTCCA
CCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGTTTGAATTTTTTA
AAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCAAGCCAATCG
TTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTTTAAAAGAGA
TTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTTTCTTTTTTT
CCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTTTGAGAAAAA
TAATACAGGTTTTAGGGCAAATTCATGGGGGAATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCCCCTATTTGT
TTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACATACCATGATT
ATTGGTGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGCGCTTTAAAATACCCTAACATTGACAT
TCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATGAAGGCGAAAGCTTTC
ATATTAATCCTTTTTCATTAGAAGATAGCGCAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATGGCAAAAGTA
GATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACCATGTATAGAAATTA
TAACGATGAAGTCAAACAAGCCAAATTCAGCAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTGTCAATTCCA
TTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGCCGAATGGAT
AGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACATAATGATGATGACGCTGGGCTTTTAGC
TTATTATGTGTTTCATAAGATGATTGATAGAGCCTTGAGAATCAATCGTGGGTTTTTATGTTTTATTGATGAGTTTAAAT
CTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGGGTCATTGTT
CTAGCCTTACAAGACATTAACCAACTTAGTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCAATTAATTTT
GTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAAAACATTTTT
TAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATAGATGTGAGC
CTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCTTATTAAACA
CTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAGAAAAGGTGC
TTTGCCCAACATGA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (211-409)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (434-501)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.073	97.666	0.46