Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   KPA27_RS08230 Genome accession   NZ_CP076517
Coordinates   1652425..1653114 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain 39565     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1647425..1658114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPA27_RS08205 (KPA27_08205) - 1647895..1648608 (-) 714 Protein_1582 NADPH-dependent oxidoreductase -
  KPA27_RS08210 (KPA27_08210) dnaI 1648605..1649504 (-) 900 WP_202847525.1 primosomal protein DnaI -
  KPA27_RS08215 (KPA27_08215) - 1649504..1650655 (-) 1152 WP_216330783.1 replication initiation/membrane attachment protein -
  KPA27_RS08220 (KPA27_08220) nrdR 1650642..1651133 (-) 492 WP_105156551.1 transcriptional regulator NrdR -
  KPA27_RS08225 (KPA27_08225) - 1651205..1652335 (-) 1131 WP_012027644.1 AI-2E family transporter -
  KPA27_RS08230 (KPA27_08230) covR 1652425..1653114 (-) 690 WP_012027645.1 winged helix-turn-helix domain-containing protein Regulator
  KPA27_RS08235 (KPA27_08235) gndA 1653196..1654623 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  KPA27_RS08240 (KPA27_08240) - 1654720..1655259 (-) 540 WP_014638519.1 DUF177 domain-containing protein -
  KPA27_RS08245 (KPA27_08245) trxB 1655269..1656186 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  KPA27_RS08250 (KPA27_08250) - 1656200..1656424 (-) 225 WP_014638521.1 DUF4059 family protein -
  KPA27_RS08255 (KPA27_08255) - 1656442..1657785 (-) 1344 WP_044759432.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=576130 KPA27_RS08230 WP_012027645.1 1652425..1653114(-) (covR) [Streptococcus suis strain 39565]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=576130 KPA27_RS08230 WP_012027645.1 1652425..1653114(-) (covR) [Streptococcus suis strain 39565]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCGTCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGCAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432