Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   KPA27_RS05330 Genome accession   NZ_CP076517
Coordinates   1040874..1042100 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain 39565     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1035874..1047100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPA27_RS05300 (KPA27_05300) - 1035903..1036127 (-) 225 WP_002934981.1 hypothetical protein -
  KPA27_RS05305 (KPA27_05305) - 1036189..1037502 (-) 1314 WP_024385202.1 excalibur calcium-binding domain-containing protein -
  KPA27_RS05310 (KPA27_05310) - 1037637..1037819 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  KPA27_RS05315 (KPA27_05315) lepA 1037869..1039701 (-) 1833 WP_044668492.1 translation elongation factor 4 -
  KPA27_RS05320 (KPA27_05320) ndk 1039797..1040210 (-) 414 WP_044668489.1 nucleoside-diphosphate kinase -
  KPA27_RS05325 (KPA27_05325) yihA 1040233..1040820 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  KPA27_RS05330 (KPA27_05330) clpX 1040874..1042100 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  KPA27_RS05335 (KPA27_05335) - 1042298..1042810 (-) 513 WP_044683343.1 dihydrofolate reductase -
  KPA27_RS05340 (KPA27_05340) - 1043152..1043991 (-) 840 WP_202847697.1 thymidylate synthase -
  KPA27_RS05345 (KPA27_05345) - 1044044..1044346 (-) 303 WP_202847696.1 hypothetical protein -
  KPA27_RS05350 (KPA27_05350) - 1044358..1044636 (-) 279 WP_012775087.1 hypothetical protein -
  KPA27_RS05355 (KPA27_05355) - 1044762..1045721 (-) 960 WP_023370402.1 ROK family glucokinase -
  KPA27_RS05360 (KPA27_05360) - 1045817..1046152 (-) 336 WP_002934966.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=576116 KPA27_RS05330 WP_002934974.1 1040874..1042100(-) (clpX) [Streptococcus suis strain 39565]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=576116 KPA27_RS05330 WP_002934974.1 1040874..1042100(-) (clpX) [Streptococcus suis strain 39565]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTAGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTATGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAGGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAGTCAAATATCCTTATGATTGGTCCGACTGGTTCAGGAAAAACCTTCCTAGCACAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGTATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATATCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGCGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAACCTTTACTAGAAACTGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574