Detailed information NTG0576113

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: KPA27_RS04500
• Genome accession: NZ_CP076517
• Coordinates: 872446..873117 (+)
• Length: 223 a.a.
• NCBI ID: WP_014637852.1
• Uniprot ID: G7SGW2
• Organism: Streptococcus suis strain 39565
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 867446..878117

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KPA27_RS04470 (KPA27_04470)	pstC	867629..868546 (+)	918	WP_002937619.1	phosphate ABC transporter permease subunit PstC	-
KPA27_RS04475 (KPA27_04475)	pstA	868536..869423 (+)	888	WP_002937616.1	phosphate ABC transporter permease PstA	-
KPA27_RS04480 (KPA27_04480)	pstB	869448..870251 (+)	804	WP_002937615.1	phosphate ABC transporter ATP-binding protein PstB	-
KPA27_RS04485 (KPA27_04485)	pstB	870263..871021 (+)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
KPA27_RS04490 (KPA27_04490)	phoU	871050..871706 (+)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
KPA27_RS04495 (KPA27_04495)	-	871872..872252 (+)	381	WP_024401461.1	hypothetical protein	-
KPA27_RS04500 (KPA27_04500)	ciaR	872446..873117 (+)	672	WP_014637852.1	response regulator transcription factor	Regulator
KPA27_RS04505 (KPA27_04505)	ciaH	873110..874489 (+)	1380	WP_024401460.1	HAMP domain-containing sensor histidine kinase	Regulator
KPA27_RS04510 (KPA27_04510)	-	874590..875819 (+)	1230	WP_216330890.1	transglutaminase domain-containing protein	-
KPA27_RS04515 (KPA27_04515)	rpsT	876034..876282 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
KPA27_RS04520 (KPA27_04520)	coaA	876341..877261 (-)	921	WP_024410470.1	type I pantothenate kinase	-
KPA27_RS04525 (KPA27_04525)	-	877370..877960 (+)	591	WP_024376492.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25245.83 Da
• Isoelectric Point: 4.2183

>NTDB_id=576113 KPA27_RS04500 WP_014637852.1 872446..873117(+) (ciaR) [Streptococcus suis strain 39565]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNSTTVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=576113 KPA27_RS04500 WP_014637852.1 872446..873117(+) (ciaR) [Streptococcus suis strain 39565]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTGGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGTATTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTTTTGAAAGAGTTACGTGAAAAAGGTGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTTTAGAGGATAAAGGCCATGGTTTTGAATTGGGAGCTGATGACTACTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACTTATGGGGACGTGACCG
TTGACTTATCGACAAACTCTACAACTGTAAATGGCGAAGAAGTTGAATTGCTAGGAAAAGAATTCGATCTACTAGTCTAC
TTCTTGCAAAATCAAAATGTTATCTTGCCAAAAACTCAAATTTTTGACCGTATTTGGGGATTTGACAGTGACACTACTAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTCGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.789	100	0.888
ciaR	Streptococcus pneumoniae D39	88.789	100	0.888
ciaR	Streptococcus pneumoniae R6	88.789	100	0.888
ciaR	Streptococcus pneumoniae TIGR4	88.789	100	0.888
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.053	100	0.386
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	36.283	100	0.368