Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   - Genome accession   NZ_AQYA01000030
Coordinates   8781..8882 (+) Length   34 a.a.
NCBI ID   - Uniprot ID   -
Organism   Streptococcus henryi DSM 19005     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context


Location: 3781..13882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F601_RS0104610 purK 4131..5213 (+) 1083 WP_018164500.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  F601_RS0104615 - 5271..5972 (+) 702 WP_248678594.1 hypothetical protein -
  F601_RS0104620 purB 6269..7567 (+) 1299 WP_018164502.1 adenylosuccinate lyase -
  F601_RS0104625 comR 7782..8693 (+) 912 WP_018164503.1 helix-turn-helix domain-containing protein Regulator
  F601_RS13375 comS 8781..8882 (+) 102 WP_018164504.1 quorum-sensing system DWW-type pheromone Regulator
  F601_RS0104635 - 8939..9187 (+) 249 WP_018164505.1 hypothetical protein -
  F601_RS0104640 ruvB 9252..10253 (+) 1002 WP_026183110.1 Holliday junction branch migration DNA helicase RuvB -
  F601_RS0104645 - 10436..10870 (+) 435 WP_018164507.1 low molecular weight protein-tyrosine-phosphatase -
  F601_RS0104650 - 10881..11261 (+) 381 WP_018164508.1 hypothetical protein -
  F601_RS0104655 - 11258..13042 (+) 1785 WP_018164509.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 34 a.a.        Molecular weight: 4079.00 Da        Isoelectric Point: 10.8472

>NTDB_id=576 8781..8882(+) (comS) [Streptococcus henryi DSM 19005]
MKKLKQYQLILLFAATVIVRTAVLLKDFDWWRIG

Nucleotide


Download         Length: 102 bp        

>NTDB_id=576 8781..8882(+) (comS) [Streptococcus henryi DSM 19005]
ATGAAAAAACTTAAACAATATCAACTAATTTTACTTTTTGCTGCCACAGTCATTGTAAGAACTGCTGTGTTACTCAAAGA
TTTTGATTGGTGGCGTATCGGT

XIP


This gene is known to encode the precursor of σX inducing peptide (XIP), which involves in competence development. The mature XIP sequence is displayed as below:

FDWWRIG


Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS315

41.935

91.176

0.382


Multiple sequence alignment