Detailed information NTG0575353

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: KMZ16_RS12845
• Genome accession: NZ_CP076445
• Coordinates: 2492533..2494863 (-)
• Length: 776 a.a.
• NCBI ID: WP_080477815.1
• Uniprot ID: -
• Organism: Bacillus subtilis subsp. subtilis strain ps4100
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2487533..2499863

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KMZ16_RS12810 (KMZ16_12710)	yqxA	2487872..2488210 (-)	339	WP_004399162.1	YqxA family protein	-
KMZ16_RS12815 (KMZ16_12715)	spoIIP	2488227..2489432 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
KMZ16_RS12820 (KMZ16_12720)	gpr	2489495..2490601 (-)	1107	WP_014480309.1	GPR endopeptidase	-
KMZ16_RS12825 (KMZ16_12725)	rpsT	2490805..2491071 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
KMZ16_RS12830 (KMZ16_12730)	holA	2491086..2492129 (-)	1044	WP_015714286.1	DNA polymerase III subunit delta	-
KMZ16_RS12835 (KMZ16_12735)	-	2492169..2492318 (-)	150	WP_003229985.1	hypothetical protein	-
KMZ16_RS12840 (KMZ16_12740)	yqzM	2492359..2492493 (+)	135	WP_003229983.1	YqzM family protein	-
KMZ16_RS12845 (KMZ16_12745)	comEC	2492533..2494863 (-)	2331	WP_080477815.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
KMZ16_RS12850 (KMZ16_12750)	comEB	2494860..2495429 (-)	570	WP_015714288.1	ComE operon protein 2	-
KMZ16_RS12855 (KMZ16_12755)	comEA	2495496..2496113 (-)	618	WP_004398514.1	competence protein ComEA	Machinery gene
KMZ16_RS12860 (KMZ16_12760)	comER	2496197..2497018 (+)	822	WP_004398597.1	late competence protein ComER	-
KMZ16_RS12865 (KMZ16_12765)	yqeM	2497084..2497827 (-)	744	WP_003229973.1	class I SAM-dependent methyltransferase	-
KMZ16_RS12870 (KMZ16_12770)	rsfS	2497824..2498180 (-)	357	WP_003229971.1	ribosome silencing factor	-
KMZ16_RS12875 (KMZ16_12775)	yqeK	2498198..2498758 (-)	561	WP_004399059.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
KMZ16_RS12880 (KMZ16_12780)	nadD	2498748..2499317 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
KMZ16_RS12885 (KMZ16_12785)	yhbY	2499329..2499619 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86623.22 Da
• Isoelectric Point: 7.1612

>NTDB_id=575353 KMZ16_RS12845 WP_080477815.1 2492533..2494863(-) (comEC) [Bacillus subtilis subsp. subtilis strain ps4100]
MMNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMVVKTPDKEKWAAAYRILSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHTISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVDVFTIMIAHPAPVLLFLFTVAIILLLMAIEKRSLSQLMITGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWHEKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPE
TPDPASKNNSSLVLWMETGVLSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQKVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=575353 KMZ16_RS12845 WP_080477815.1 2492533..2494863(-) (comEC) [Bacillus subtilis subsp. subtilis strain ps4100]
GTGATGAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGGTGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCTGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGAGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATTCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATACCATATCATTCACAAACAGCCTTTTGCCTCCTGATTCGGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAGGACGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTTTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATTCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGACAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTTCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTTGCGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGATAACCGGCGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCACGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
ACACCTGATCCGGCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGTTCTGAGCTGGATTTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAAAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	97.68	100	0.977