Detailed information NTG0574570

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: KM843_RS16550
• Genome accession: NZ_CP076291
• Coordinates: 3377127..3378290 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain US1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3372127..3383290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KM843_RS16520 (KM843_16520)	-	3372392..3372811 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
KM843_RS16525 (KM843_16525)	comFC	3372885..3373574 (-)	690	WP_197197403.1	double zinc ribbon domain-containing protein	Machinery gene
KM843_RS16530 (KM843_16530)	-	3373580..3373864 (-)	285	WP_007407481.1	competence protein ComFB	-
KM843_RS16535 (KM843_16535)	comFA	3373922..3375307 (-)	1386	WP_012118573.1	DEAD/DEAH box helicase	Machinery gene
KM843_RS16540 (KM843_16540)	-	3375415..3376263 (-)	849	WP_003151387.1	DegV family protein	-
KM843_RS16545 (KM843_16545)	degU	3376361..3377050 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
KM843_RS16550 (KM843_16550)	degS	3377127..3378290 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
KM843_RS16555 (KM843_16555)	-	3378513..3379160 (+)	648	WP_007614107.1	YigZ family protein	-
KM843_RS16560 (KM843_16560)	-	3379165..3380385 (+)	1221	WP_012118574.1	LCP family protein	-
KM843_RS16565 (KM843_16565)	-	3380484..3381560 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
KM843_RS16570 (KM843_16570)	-	3381693..3382889 (-)	1197	WP_012118575.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=574570 KM843_RS16550 WP_007407484.1 3377127..3378290(-) (degS) [Bacillus velezensis strain US1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=574570 KM843_RS16550 WP_007407484.1 3377127..3378290(-) (degS) [Bacillus velezensis strain US1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGGGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951