Detailed information NTG0573522

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: MPF87_RS07645
• Genome accession: NZ_CP094052
• Coordinates: 1580676..1583252 (+)
• Length: 858 a.a.
• NCBI ID: WP_245012638.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain Hpfe126
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1575676..1588252

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MPF87_RS07610 (MPF87_07610)	-	1577163..1577939 (+)	777	WP_245012634.1	CAAX protease	-
MPF87_RS07615 (MPF87_07615)	-	1577927..1578445 (+)	519	Protein_1486	restriction endonuclease subunit S	-
MPF87_RS07620 (MPF87_07620)	-	1578501..1579289 (+)	789	WP_245012635.1	integrase	-
MPF87_RS07625 (MPF87_07625)	-	1579393..1579872 (+)	480	WP_245012636.1	hypothetical protein	-
MPF87_RS07630 (MPF87_07630)	comB2	1579869..1580153 (+)	285	WP_000736106.1	TrbC/VirB2 family protein	Machinery gene
MPF87_RS07635 (MPF87_07635)	comB3	1580165..1580428 (+)	264	WP_208371262.1	competence protein ComB	Machinery gene
MPF87_RS07640 (MPF87_07640)	-	1580440..1580676 (+)	237	WP_245012637.1	hypothetical protein	-
MPF87_RS07645 (MPF87_07645)	comB4	1580676..1583252 (+)	2577	WP_245012638.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
MPF87_RS07650 (MPF87_07650)	-	1583254..1583388 (+)	135	WP_021301032.1	hypothetical protein	-
MPF87_RS07655 (MPF87_07655)	-	1583381..1584554 (+)	1174	Protein_1494	VirB8/TrbF family protein	-
MPF87_RS07660 (MPF87_07660)	-	1584551..1586218 (+)	1668	WP_180475079.1	TrbG/VirB9 family P-type conjugative transfer protein	-
MPF87_RS07665 (MPF87_07665)	comB10	1586215..1587417 (+)	1203	WP_140482552.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98828.77 Da
• Isoelectric Point: 8.7585

>NTDB_id=573522 MPF87_RS07645 WP_245012638.1 1580676..1583252(+) (comB4) [Helicobacter pylori strain Hpfe126]
MFENALKYCKEKAIDLLTGFVPKTYSMAQECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLIQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSNKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECTLNLVLRAKSRAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGTTGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSASNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEYYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALRINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLA

Nucleotide

• Length: 2577 bp

>NTDB_id=573522 MPF87_RS07645 WP_245012638.1 1580676..1583252(+) (comB4) [Helicobacter pylori strain Hpfe126]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GGCACAGGAGTGCAATATTTTAGGTTTGTATGATGATACTTTCATTATTACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATACAAAAAGACTTAGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCTATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAACAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTACCTTAAACTTAGTTTTAAGAGCTAAAAGTAGAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCACAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGCGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATGAAGGCG
AAAGCTTTCATATTAATCCTTTTTCATTAGAAGATAGCGCAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCTAAATTTAGCAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAATACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGCTTATTATGTCTTTCATAAGATGATTGATAGAGCCTTGAGAATCAATCGTGGGTTTTTGTGTTTTATTGATG
AGTTTAAATCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTGATTGTTTTAGCCTTACAAGACATTAACCAACTTAGTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAACACTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTGCCTAA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.73	98.019	0.458