Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   MO978_RS02250 Genome accession   NZ_CP093959
Coordinates   433337..434779 (-) Length   480 a.a.
NCBI ID   WP_014570382.1    Uniprot ID   -
Organism   Lactococcus lactis strain FAM 17919     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 428337..439779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MO978_RS02225 (MO978_02230) nox 428369..429709 (+) 1341 WP_014570381.1 H2O-forming NADH oxidase -
  MO978_RS02230 (MO978_02235) ssbB 429799..430188 (+) 390 WP_010905314.1 single-stranded DNA-binding protein Machinery gene
  MO978_RS02235 (MO978_02240) groES 430308..430592 (+) 285 WP_003131589.1 co-chaperone GroES -
  MO978_RS02240 (MO978_02245) groL 430680..432308 (+) 1629 WP_003131585.1 chaperonin GroEL -
  MO978_RS02245 (MO978_02250) vicX 432354..433166 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  MO978_RS02250 (MO978_02255) vicK 433337..434779 (-) 1443 WP_014570382.1 cell wall metabolism sensor histidine kinase WalK Regulator
  MO978_RS02255 (MO978_02260) yycF 434772..435473 (-) 702 WP_003131580.1 response regulator YycF -
  MO978_RS02260 (MO978_02265) tmk 435651..436286 (+) 636 WP_003131575.1 dTMP kinase -
  MO978_RS02265 (MO978_02270) - 436419..437279 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  MO978_RS02270 (MO978_02275) yaaT 437331..438113 (+) 783 WP_003131572.1 stage 0 sporulation family protein Regulator
  MO978_RS02275 (MO978_02280) yabA 438106..438432 (+) 327 WP_003131570.1 DNA replication initiation control protein YabA -
  MO978_RS02280 (MO978_02285) rsmI 438432..439307 (+) 876 WP_010905318.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  MO978_RS02285 (MO978_02290) - 439384..439575 (-) 192 WP_003131566.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54693.11 Da        Isoelectric Point: 4.5889

>NTDB_id=573063 MO978_RS02250 WP_014570382.1 433337..434779(-) (vicK) [Lactococcus lactis strain FAM 17919]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQINDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKITDQYNFYDLLEKEPEITIETHDSGNESISLHIKFSLFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=573063 MO978_RS02250 WP_014570382.1 433337..434779(-) (vicK) [Lactococcus lactis strain FAM 17919]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATAAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCACTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTACTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATTC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTTCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGGATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTCTC
TATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

PAS domain (PAS_9)

(124-220)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.319

86.875

0.446
  micB Streptococcus pneumoniae Cp1015

47.523

92.5

0.44