Detailed information NTG0572139

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: KM132_RS17300
• Genome accession: NZ_CP076119
• Coordinates: 3533515..3534678 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain NZ4
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3528515..3539678

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KM132_RS17270 (KM132_17270)	-	3528780..3529199 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
KM132_RS17275 (KM132_17275)	comFC	3529273..3529962 (-)	690	WP_199449054.1	ComF family protein	Machinery gene
KM132_RS17280 (KM132_17280)	-	3529968..3530252 (-)	285	WP_003151389.1	competence protein ComFB	-
KM132_RS17285 (KM132_17285)	comFA	3530310..3531695 (-)	1386	WP_029972824.1	DEAD/DEAH box helicase	Machinery gene
KM132_RS17290 (KM132_17290)	-	3531803..3532651 (-)	849	WP_003151387.1	DegV family protein	-
KM132_RS17295 (KM132_17295)	degU	3532749..3533438 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
KM132_RS17300 (KM132_17300)	degS	3533515..3534678 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
KM132_RS17305 (KM132_17305)	-	3534901..3535548 (+)	648	WP_007614107.1	YigZ family protein	-
KM132_RS17310 (KM132_17310)	-	3535553..3536767 (+)	1215	WP_103526592.1	LCP family protein	-
KM132_RS17315 (KM132_17315)	-	3536866..3537942 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
KM132_RS17320 (KM132_17320)	-	3538075..3539271 (-)	1197	WP_060673980.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=572139 KM132_RS17300 WP_007407484.1 3533515..3534678(-) (degS) [Bacillus velezensis strain NZ4]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=572139 KM132_RS17300 WP_007407484.1 3533515..3534678(-) (degS) [Bacillus velezensis strain NZ4]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTTATCATTAAGGACAACGGAAAAGGTTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951