Detailed information NTG0057206

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SAI2T2_RS04620
• Genome accession: NC_020564
• Coordinates: 951060..952046 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus subsp. aureus ST228
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 946060..957046

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAI2T2_RS04595 (SAI2T2_1007010)	opp4B	946274..947236 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
SAI2T2_RS04600 (SAI2T2_1007020)	opp4C	947248..948129 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
SAI2T2_RS04605 (SAI2T2_1007030)	trpS	948171..949160 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
SAI2T2_RS04610	spxA	949454..949849 (+)	396	WP_041174200.1	transcriptional regulator SpxA	-
SAI2T2_RS04615 (SAI2T2_1007040)	mecA	950220..950939 (+)	720	WP_001217728.1	adaptor protein MecA	-
SAI2T2_RS04620 (SAI2T2_1007050)	coiA	951060..952046 (+)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
SAI2T2_RS04625 (SAI2T2_1007060)	pepF	952094..953902 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
SAI2T2_RS04630 (SAI2T2_1007070)	yjbH	954362..955168 (-)	807	WP_015445788.1	protease adaptor protein YjbH	-
SAI2T2_RS04635	-	955191..955556 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
SAI2T2_RS04640 (SAI2T2_1007080)	-	955660..956253 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
SAI2T2_RS04645	-	956439..956786 (+)	348	WP_001242109.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=57206 SAI2T2_RS04620 WP_000959282.1 951060..952046(+) (coiA) [Staphylococcus aureus subsp. aureus ST228]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=57206 SAI2T2_RS04620 WP_000959282.1 951060..952046(+) (coiA) [Staphylococcus aureus subsp. aureus ST228]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976