Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KMZ21_RS02475 Genome accession   NZ_CP076105
Coordinates   526683..527252 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus subsp. aureus RN4220     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 521683..532252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KMZ21_RS02450 (KMZ21_02450) cysE 522896..523543 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  KMZ21_RS02455 (KMZ21_02455) cysS 523527..524927 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  KMZ21_RS02460 (KMZ21_02460) - 524920..525324 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  KMZ21_RS02465 (KMZ21_02465) rlmB 525332..526078 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KMZ21_RS02470 (KMZ21_02470) - 526078..526602 (+) 525 WP_000664738.1 NYN domain-containing protein -
  KMZ21_RS02475 (KMZ21_02475) sigH 526683..527252 (+) 570 WP_000872873.1 RNA polymerase sigma factor Regulator
  KMZ21_RS02480 (KMZ21_02480) rpmG 527367..527510 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  KMZ21_RS02485 (KMZ21_02485) secE 527566..527748 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KMZ21_RS02490 (KMZ21_02490) nusG 527761..528309 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  KMZ21_RS02495 (KMZ21_02495) rplK 528490..528912 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  KMZ21_RS02500 (KMZ21_02500) rplA 529120..529812 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  KMZ21_RS02505 (KMZ21_02505) rplJ 530084..530584 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  KMZ21_RS02510 (KMZ21_02510) rplL 530627..530995 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KMZ21_RS02515 (KMZ21_02515) - 531170..531778 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=571861 KMZ21_RS02475 WP_000872873.1 526683..527252(+) (sigH) [Staphylococcus aureus subsp. aureus RN4220]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=571861 KMZ21_RS02475 WP_000872873.1 526683..527252(+) (sigH) [Staphylococcus aureus subsp. aureus RN4220]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984