Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MLA23_RS08710 Genome accession   NZ_CP093317
Coordinates   1855140..1855796 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain HUM3355     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1850140..1860796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MLA23_RS08680 (MLA23_08670) dcyD 1851020..1852006 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  MLA23_RS08685 (MLA23_08675) tcyL 1852021..1852689 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  MLA23_RS08690 (MLA23_08680) tcyN 1852686..1853438 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MLA23_RS08695 (MLA23_08685) sdiA 1853668..1854390 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  MLA23_RS08700 (MLA23_08690) yecF 1854457..1854681 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  MLA23_RS08705 (MLA23_08695) yecU 1854668..1854844 (-) 177 WP_000590347.1 protein YecU -
  MLA23_RS25105 - 1854927..1854998 (-) 72 Protein_1700 transcriptional regulator -
  MLA23_RS08710 (MLA23_08700) letA 1855140..1855796 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MLA23_RS08715 (MLA23_08705) uvrC 1855793..1857625 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  MLA23_RS08720 (MLA23_08710) pgsA 1857682..1858230 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MLA23_RS08740 (MLA23_08730) yecA 1858880..1859545 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=571316 MLA23_RS08710 WP_000611335.1 1855140..1855796(+) (letA) [Escherichia coli strain HUM3355]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=571316 MLA23_RS08710 WP_000611335.1 1855140..1855796(+) (letA) [Escherichia coli strain HUM3355]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486