Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MNY24_RS09425 Genome accession   NZ_CP093226
Coordinates   1973772..1974428 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC-16-35     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1968772..1979428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MNY24_RS09395 dcyD 1969651..1970637 (+) 987 WP_039023114.1 D-cysteine desulfhydrase -
  MNY24_RS09400 tcyL 1970652..1971320 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  MNY24_RS09405 tcyN 1971317..1972069 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MNY24_RS09410 sdiA 1972299..1973021 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  MNY24_RS09415 yecF 1973089..1973313 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  MNY24_RS09420 yecU 1973300..1973476 (-) 177 WP_000590344.1 protein YecU -
  MNY24_RS26015 - 1973514..1973630 (-) 117 WP_001302039.1 hypothetical protein -
  MNY24_RS09425 letA 1973772..1974428 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MNY24_RS09430 uvrC 1974425..1976257 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  MNY24_RS09435 pgsA 1976314..1976862 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MNY24_RS09455 yecA 1977511..1978176 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=570710 MNY24_RS09425 WP_000611328.1 1973772..1974428(+) (letA) [Escherichia coli strain EC-16-35]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=570710 MNY24_RS09425 WP_000611328.1 1973772..1974428(+) (letA) [Escherichia coli strain EC-16-35]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482