Detailed information NTG0056893

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAI1T1_RS13465
• Genome accession: NC_020529
• Coordinates: 2657745..2658632 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus subsp. aureus ST228
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2652745..2663632

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAI1T1_RS15225	-	2652764..2652856 (+)	93	WP_010956583.1	hypothetical protein	-
SAI1T1_RS13435 (SAI1T1_2019590)	-	2652964..2653461 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAI1T1_RS15230	-	2653471..2653731 (-)	261	WP_001791974.1	hypothetical protein	-
SAI1T1_RS15235	-	2654113..2654226 (-)	114	Protein_2554	hypothetical protein	-
SAI1T1_RS13455 (SAI1T1_2019600)	-	2654885..2656885 (-)	2001	WP_000776751.1	ABC transporter permease	-
SAI1T1_RS13460 (SAI1T1_2019610)	-	2656882..2657637 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAI1T1_RS13465 (SAI1T1_2019620)	braS	2657745..2658632 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAI1T1_RS13470 (SAI1T1_2019630)	braR	2658643..2659308 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAI1T1_RS13475	-	2659334..2659534 (-)	201	WP_000604730.1	hypothetical protein	-
SAI1T1_RS13485 (SAI1T1_2019640)	-	2659732..2661156 (+)	1425	WP_015445964.1	alkaline phosphatase	-
SAI1T1_RS16095	-	2661226..2661336 (+)	111	Protein_2561	hypothetical protein	-
SAI1T1_RS13490 (SAI1T1_2019650)	-	2661439..2661894 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAI1T1_RS13495 (SAI1T1_2019660)	-	2662139..2662900 (-)	762	WP_015445965.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=56893 SAI1T1_RS13465 WP_000143425.1 2657745..2658632(-) (braS) [Staphylococcus aureus subsp. aureus ST228]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=56893 SAI1T1_RS13465 WP_000143425.1 2657745..2658632(-) (braS) [Staphylococcus aureus subsp. aureus ST228]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1