Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MJ614_RS04670 Genome accession   NZ_CP092647
Coordinates   499550..500206 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC5502     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 494550..505206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MJ614_RS04640 yecA 495802..496467 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  MJ614_RS04660 pgsA 497116..497664 (-) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MJ614_RS04665 uvrC 497721..499553 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  MJ614_RS04670 letA 499550..500206 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MJ614_RS26855 - 500348..500419 (+) 72 Protein_543 transcriptional regulator -
  MJ614_RS04675 yecU 500502..500678 (+) 177 WP_000590347.1 protein YecU -
  MJ614_RS04680 yecF 500665..500889 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  MJ614_RS04685 sdiA 500956..501678 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  MJ614_RS04690 tcyN 501908..502660 (-) 753 WP_001272987.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MJ614_RS04695 tcyL 502657..503325 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  MJ614_RS04700 dcyD 503340..504326 (-) 987 WP_001128219.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=567669 MJ614_RS04670 WP_000611335.1 499550..500206(-) (letA) [Escherichia coli strain EC5502]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=567669 MJ614_RS04670 WP_000611335.1 499550..500206(-) (letA) [Escherichia coli strain EC5502]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486