Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MJJ13_RS08930 Genome accession   NZ_CP092449
Coordinates   1857268..1857924 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli isolate TKEC21-17     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1852268..1862924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MJJ13_RS08900 (MJJ13_08900) dcyD 1853147..1854133 (+) 987 WP_001565616.1 D-cysteine desulfhydrase -
  MJJ13_RS08905 (MJJ13_08905) tcyL 1854148..1854816 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  MJJ13_RS08910 (MJJ13_08910) tcyN 1854813..1855565 (+) 753 WP_032247644.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MJJ13_RS08915 (MJJ13_08915) sdiA 1855795..1856517 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  MJJ13_RS08920 (MJJ13_08920) yecF 1856585..1856809 (-) 225 WP_000106473.1 DUF2594 family protein YecF -
  MJJ13_RS08925 (MJJ13_08925) yecU 1856796..1856972 (-) 177 WP_000590344.1 protein YecU -
  MJJ13_RS23410 - 1857010..1857126 (-) 117 WP_001302039.1 hypothetical protein -
  MJJ13_RS08930 (MJJ13_08930) letA 1857268..1857924 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MJJ13_RS08935 (MJJ13_08935) uvrC 1857921..1859753 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  MJJ13_RS08940 (MJJ13_08940) pgsA 1859810..1860358 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MJJ13_RS08960 (MJJ13_08960) yecA 1861008..1861673 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=565217 MJJ13_RS08930 WP_000611328.1 1857268..1857924(+) (letA) [Escherichia coli isolate TKEC21-17]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=565217 MJJ13_RS08930 WP_000611328.1 1857268..1857924(+) (letA) [Escherichia coli isolate TKEC21-17]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482