Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SITYG_RS02485 Genome accession   NZ_AP014880
Coordinates   480590..481222 (+) Length   210 a.a.
NCBI ID   WP_009568138.1    Uniprot ID   T1ZG08
Organism   Streptococcus intermedius strain TYG1620     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 475590..486222
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS02465 (SITYG_04660) - 476024..476764 (+) 741 WP_003073671.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SITYG_RS02470 (SITYG_04670) stkP 476761..478635 (+) 1875 WP_096362578.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SITYG_RS02475 (SITYG_04690) liaF 478898..479596 (+) 699 WP_009568136.1 cell wall-active antibiotics response protein LiaF -
  SITYG_RS02480 (SITYG_04700) - 479593..480588 (+) 996 WP_096362579.1 sensor histidine kinase -
  SITYG_RS02485 (SITYG_04710) vraR 480590..481222 (+) 633 WP_009568138.1 response regulator transcription factor Regulator
  SITYG_RS02490 (SITYG_04720) - 481262..482662 (+) 1401 WP_003078255.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SITYG_RS02495 (SITYG_04730) - 482664..483056 (+) 393 WP_096362580.1 S1 RNA-binding domain-containing protein -
  SITYG_RS02500 (SITYG_04740) - 483176..483493 (-) 318 WP_003073656.1 DUF960 domain-containing protein -
  SITYG_RS02505 (SITYG_04750) - 483613..484146 (-) 534 WP_003073655.1 DUF402 domain-containing protein -
  SITYG_RS02510 (SITYG_04760) recX 484233..485009 (-) 777 WP_009568142.1 recombination regulator RecX Regulator
  SITYG_RS02515 (SITYG_04770) - 485073..485849 (-) 777 WP_096362581.1 aminoglycoside 3'-phosphotransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23710.39 Da        Isoelectric Point: 4.8916

>NTDB_id=56498 SITYG_RS02485 WP_009568138.1 480590..481222(+) (vraR) [Streptococcus intermedius strain TYG1620]
MQILLVDDHEMVRLGLKSYLDVQNDVDMVVEASNGCEGVEKALSLRPDVIMMDIVMPKMNGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEELTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=56498 SITYG_RS02485 WP_009568138.1 480590..481222(+) (vraR) [Streptococcus intermedius strain TYG1620]
ATGCAGATTTTATTAGTAGATGATCATGAAATGGTGCGACTTGGTTTGAAGAGCTATTTGGATGTACAAAATGATGTTGA
TATGGTGGTAGAAGCTTCAAATGGTTGTGAAGGGGTGGAAAAGGCTCTGTCATTACGACCAGATGTGATAATGATGGATA
TTGTCATGCCTAAAATGAATGGGATTGAAGCTACACTTGCTATTTTAAAAGAATGGCCTGAAGCTAAAATTCTTATTTTG
ACTTCTTATTTAGATAATGAAAAAATTTACCCAGTTTTAGATGCAGGGGCTAAAGGATACATGCTTAAAACATCTAGTGC
TGACGATATCTTACGAGCAGTTCGAAAGGTAGCAAAGGGTGAACTTGCTATTGAAACAGAGGTCAGTCAGAAAGTGGAAT
ACCATCGAAATCATATTGAATTACATGAAGAGCTAACAGCGCGTGAGCGCGATATTTTAGGTCTATTAGCAAAAGGGTAT
GAAAATCAACGGATAGCAGATGAGTTGTTTATTTCGTTGAAGACTGTTAAAACACATGTATCTAATATCTTATCAAAATT
AGAAGTAAGTGATCGGACACAAGCTGTTGTTTACGCCTTTCAGCACCACCTTGTCCCACAAGATGACATTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZG08

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414

Multiple sequence alignment